[17 Aug 2017 | ]
NanoSight unique contributions to today’s hottest research fields

Being involved with the NanoSight products gives us visibility over a wide range of research areas that have a direct benefit to science and humanity. It is quite exciting to feel we are contributing to advancing science in these fields.
I was prompted to do a quick review of recent publications to see where NanoSight systems are being used after reading a recent article by Lara Aqrawi on characterizing extracellular vesicles in tears and saliva as a non-invasive diagnostic method for primary Sjögren’s syndrome (pSS) patients. Nanoparticle tracking analysis was conducted …

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Customer experience, Nanoparticle Tracking Analysis, Nanosight, Particle concentration »

[17 Aug 2017 | ]
NanoSight unique contributions to today’s hottest research fields

Being involved with the NanoSight products gives us visibility over a wide range of research areas that have a direct benefit to science and humanity. It is quite exciting to feel we are contributing to advancing science in these fields.
I was prompted to do a quick review of recent publications to see where NanoSight systems are being used after reading a recent article by Lara Aqrawi on characterizing extracellular vesicles in tears and saliva as a non-invasive diagnostic method for primary Sjögren’s syndrome (pSS) patients. Nanoparticle tracking analysis was conducted …

Read the full story »

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[10 Aug 2017 | ]
Key factors when considering a benchtop X-ray diffractometer

Having managed X-ray diffraction labs at previous jobs and in grad school, we know that there are a number of factors to consider when the time comes to add or replace an X-ray diffraction (XRD) system in your lab. Benchtop XRD systems may be a compact and cost-effective alternative to floor standing systems. Deciding which factors are key requirements for your needs will help you select a Benchtop system ideal for your situation.
1. Determine what level of performance is acceptable for your application
One of the key aspects of system performance …

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Dynamic Light Scattering, Electrophoretic light scattering, Laser Diffraction, Particle size, Zeta potential, Zetasizer »

[3 Aug 2017 | ]
Parenterals: What are lipid emulsions?

Intralipid-Lipid emulsions

Lipid emulsions are administered intravenously for a variety of purposes:

To help feed patients with temporary difficulty in ingesting food orally
For better transport of lipophilic drugs (fat-friendly active ingredient (API) which is not soluble in water)
For controlled release of drugs (size related to uptake and retention)
To decreasing adverse reactions to drugs
To improve targeting of drugs
In emerging gene therapies for cellular and gene delivery, and personalized medicine

Control and understanding of colloidal properties – such as droplet size and zeta potential – enable the design and optimization of appropriately stable emulsions. The …

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Laser Diffraction, Mastersizer, Particle size, Tech Talk »

[1 Aug 2017 | ]
The Mysterious Case of the Musca Domestica Contaminant

Just when I thought I’d seen everything that could contaminate the background, a user sent me this picture! The Musca Domestica (common housefly) was attracted by certain aromatics used in testing and seems to have entered the measurement cell through an empty Hydro EV over a weekend. Unfortunately, it became wedged within the measurement cell and did not survive the experience.

The most important message from the Mastersizer training courses I give is to make sure you have a good background before you start. Laser diffraction is a background subtracted technique: …

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