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Jason Corbett

Dynamic Light Scattering, Tech Talk, Zeta potential, Zetasizer »

[10 Jul 2018 | ]

Dynamic light scattering (DLS) is widely used for ensemble characterization of hydrodynamic particle size, but I have a number of frustrations with the technique.
We measure our valuable samples in low concentrations and in very small volumes, so we use expensive, low volume, glass cells, which are optically superior to disposable plastic cuvettes, but we spend far too much time cleaning them, significantly reducing the productivity of our group.
Also, our samples range from monodisperse proteins to polymeric nanoparticles to liposomes, ranging from the nano-scale into the micro-scale and we need to …

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