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Chemical identification

Advanced particle characterization by Raman spectroscopy.

Chemical identification, Image Analysis, Meet the Experts, Morphologi G3-ID, Particle shape, Raman spectroscopy »

[29 Sep 2017 | ]

I have just come back from presenting my talk ‘Application of Morphologically-Directed Raman Spectroscopy in deformulation and in vitro bioequivalence studies’ at the pharma focus session of Powtech 2017.
The talk indicated how there are still many drug products that have come of patent but do not yet have generic equivalents available and how there is a drive from the regulatory bodies to make health care more accessible and so they are producing many guidance documents to help address this.
I gave an overview of a proposed workflow for developing generic drug …

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Archimedes, Binding affinity and Kd, Chemical identification, Differential Scanning Calorimetry, Dynamic Light Scattering, Gel permeation chromatography, Image Analysis, Label-free analysis, MicroCal, Microcalorimetry, Morphologi G3-ID, Nanoparticle Tracking Analysis, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Raman spectroscopy, Resonant mass measurement, Rheology, Size Exclusion Chromatography, Taylor Dispersion Analysis, Tech Talk, Viscosizer TD, Viscotek, Zetasizer »

[21 Sep 2017 | ]

I know this sounds like the beginning of a bad joke, but in this case, it was actually the beginning of the 2017 Colorado Protein Stability Conference, held in July at Beaver Run Resort in Breckenridge, Colorado. In attendance was a range of scientists and researchers from all over the world, with one common subject in mind: Protein Stability.

One of the highlights of this conference was the pre-conference workshop. This was a free workshop for all attendees of the conference, which was sponsored by Malvern Panalytical. The workshop included a range …

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Chemical identification, Image Analysis, Meet the Experts, Morphologi G3, Morphologi G3-ID, Particle shape »

[7 Sep 2017 | ]

Standing at just under 3800 m tall with its distinctive symmetrical cone-shaped peak, the majestic Mount Fuji, or Fujisan (富士山) as it is known locally, is one of the most iconic symbols of Japan.
Therefore, it seemed only appropriate that whilst on secondment in Malvern’s Tokyo application lab, I should attempt to reach the summit of this famous volcano and, in something of a cliché, watch the sunrise from the highest peak in the Land of the Rising Sun.
There is only a short window each year in which one is permitted …

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Chemical identification, Image Analysis, Morphologi G3-ID »

[25 Jul 2017 | ]

Why is it that structures built in Roman times have resisted the elements for thousands of years when more modern structures have suffered?
This was a question posed in a recent BBC news story ‘Scientists explain ancient Rome’s long-lasting concrete’ that caught my eye since we have pondered the question here at Malvern before as you can see in this application note “Component Characterization of Cements” where the Morphologi G3-ID was used to study and compare the composition of different cements.

How is the concrete made?
Ancient structures are built using concrete made from …

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Archimedes, Chemical identification, Label-free analysis, Malvern Panalytical Events, MicroCal, Microcalorimetry, Molecular size, Molecular structure, Molecular weight, Morphologi G3-ID, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Protein Mobility, Viscosizer TD, Zeta potential, Zetasizer »

[16 May 2017 | ]

With Pre-Conference Workshop on Biophysical Characterization and Particle Analysis
 

Date: July 17th – 20th.
We at Malvern know that protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that researchers from all the relevant areas can join to discuss the critical issues in the field. The 2017 Colorado Protein Stability Conference provides a unique forum for this exchange of information. The topics to be covered include protein folding, dynamics and thermodynamic stability; amyloidosis and protein aggregation; and stability, formulation, analysis and processing …

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Chemical identification, Image Analysis, Laser Diffraction, Malvern Panalytical Events, Mastersizer, Morphologi G3-ID, Particle shape, Particle size, Raman spectroscopy »

[29 Jun 2016 | ]

Over the past week I’ve had a lot of fun working with Malvern’s team in China to deliver a series of seminars designed to help researchers engaged in pharmaceutical product development. These meetings focused on how Malvern’s material characterization systems can help those developing and manufacturing oral solid dose formulations. During the seminar series, we had the privilege of meeting with well over 200 customers, providing us with the chance to learn about the challenges they are facing in product development, as they seek to select APIs and excipients which …

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Chemical identification, Image Analysis, Laser Diffraction, Mastersizer, Meet the Experts, Morphologi G3-ID, Particle shape, Particle size, Raman spectroscopy, Tech Talk »

[20 Jun 2016 | ]

Component-specific Particle Size
Follow that particle!

I’ve always thought it would be great to be the innocent driver in a movie chase scene who has to respond to the hero’s demand to ‘Follow that car’ as they try to keep tabs on the villain. I always imaged that this would unlock the silent racing driver within me, giving me the excuse to forget about speed limits and drive at the limits of my car’s performance. I’d also get the chance to practice my handbrake turns!
Although I have never been engaged in a …

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Chemical identification, Kinexus, Morphologi G3-ID, Particle shape, Spraytec, Tech Talk »

[14 Jun 2016 | ]

MDRS Technology
Finally!  After what has felt like one of the wettest and longest winters in memory here in the UK, we’re now heading into the long, mellow days of midsummer.
But casting its miserable shadow over the barbecues, school holidays and paddling pools is the dreaded allergy season.  As one of the downsides of life in our “green and pleasant land”, during June we are hit hard by the combined impact of pollen from trees, grasses and weeds.
Many of us are now taking a daily antihistamine of some sort, and others …

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Chemical identification, Customer experience, Morphologi G3-ID, Particle shape, Raman spectroscopy, Tech Talk »

[27 Nov 2014 | ]

Hello!  A few months ago I blogged about my up and coming visit to Australia and I promised to let you know if I made it to the top of the Sydney Harbour bridge – I am not sure where the time as flown to since then but I thought it was about time I let you know how the trip went.
One of the reasons I headed down under was to give 12 seminars; 4 each in Melbourne, Sydney and Brisbane – the team at ATA Scientific did a great …

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Chemical identification, Mastersizer, Meet the Experts, Morphologi G3, Morphologi G3-ID »

[14 May 2014 | ]

I am really looking forward to my next trip as it is somewhere I have never been before. The sale of a Morphologi G3-ID in Australia to Southern Cross University has finally given me the opportunity to go and visit which is very exciting!
I will be heading over to give training on the newly installed system at the Southern Cross Geoscience research center. The group undertakes innovative research that contributes to the understanding and improved management of land and water resources with particular reference to the impact of human activity.
To …

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Chemical identification, Malvern Panalytical Events, Morphologi G3, Raman spectroscopy »

[21 Feb 2014 | ]

A new year brings a new job for me as Product Manager for Malvern’s Analytical Imaging range. This brings exciting challenges to think about possible new products and find new applications for our current ones. So that brings me over to Seattle to the American Academy of Forensic Science 66th Annual Scientific Meeting.
On Monday I attended the ‘Applications of Raman Spectroscopy for trace evidence examinations’ workshop chaired by Patrick Buzzini of West Virginia University. There was a really informative introduction to Raman spectroscopy given by Edward M Suzuki which explained …

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Chemical identification, Particle shape, Particle size »

[9 Dec 2011 | ]
Edinburgh works its magic again

As we come to the end of another fascinating and truly illuminating Drug Delivery to the Lungs conference here in Edinburgh, I’m delighted to report that this year the snow has stayed on the hills, but it has been rather windy. I’m very much hoping it will calm down so I have  a trouble-free trip as I head south this afternoon.
Imaging in OINDP
Anne Virden and I love coming to DDL as there are so many opportunities to talk to people who are doing really interesting work in inhaled product development. Many people …

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