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Particle shape

Particle shape can have a significant impact upon the performance and process handling of many particulate materials.

Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape, Particle size »

[8 May 2018 | ]

Interested in the size, shape and chemical identity of your particles?
 
Have an application where particle shape plays a critical role, such as particle packing or adhesion to surfaces?
 
Need forensic evaluation of a failed batch, or identification of a contaminant in the process line?
 
A recent value analysis shows that a customer’s use of MDRS for component-specific particle characterization helped them save up to $500,000 when compared to conventional analysis.
Malvern Panalytical
117 Flanders Road, Westborough, MA
Thursday, May 10 2018, 8:30 – 1:30
This seminar is your chance to learn more about Morphological Imaging for the …

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Elemental analysis, Empyrean, Epsilon, Français, Image Analysis, Malvern Panalytical Events, Mastersizer, Meet the Experts, Particle shape, Particle size, X'Pert3, X-Ray Diffraction (XRD), X-Ray Fluorescence (XRF), Zeta potential »

[22 Mar 2018 | ]

Malvern Panalytical sera à Forum Labo Biotech Lyon, Stand A12, (en bas des escalators) les 28 et 29 mars 2018. Forum Labo est le salon des fournisseurs de matériels et services pour le laboratoire.
Venez voir en exclusivité le nouveau granulomètre et analyseur de forme Morphologi 4 ainsi que 3 autres nouveaux instruments inédits !
Vous pourrez découvrir :

Un nouveau rhéomètre avec de nouvelles fonctionnalités,
Des passeurs d’échantillons pour Zetasizer, Nanosight NS300,

Un nouveau spectromètre de fluorescence X Epsilon 4 de la gamme Panalytical.

Toute notre équipe de spécialistes d’application sera présente, prête à répondre à toutes vos questions …

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Chemical identification, Image Analysis, Inside Malvern Panalytical, Morphologi, Particle shape »

[27 Feb 2018 | ]

What a wonderful boost we had to the February 14th launch of the new Morphologi 4 and Morphologi 4-ID when we found out that these systems were winners of an iF (Industrie Forum) Design 2018 award!  As the Project Manager responsible for Visual Brand Language on the Morphologi 4 range, I work closely with the design teams both here at Malvern Panalytical, and also at DCA Design, the agency which helped bring our vision for the instruments to life!
So, what are some of the design changes we implemented in the …

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Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape »

[14 Feb 2018 | ]

東京へ ようこそ!  Welcome to Tokyo!  I’m very excited to return to Japan with the launch of the new Morphologi 4 range here at Tokyo Big Sight.  We’re at Nanotech 2018, and the additive manufacturing technology exhibition running concurrently – but more on that later.
My return to Japan with the Morphologi 4 also marks the completion of a personal journey, which started almost three years ago when I seconded to our Tokyo office to learn more about the customer applications of the previous Morphologi platform, the G3. (In fact, if you tune in to …

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Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape »

[13 Feb 2018 | ]

As I find myself surrounded by snow in Paris – the city of love – I’ve received news from my colleague, Sarennah Longworth-Cook, who has just been measuring chocolate on the new Morphologi 4 using the new Sharp Edge measurement mode.  How apt, since we’ll be launching the new Morphologi 4 range on Valentine’s Day!
So, what can Morphologi 4 tell us about our delicious chocolatey treats?

I know we don’t all think about this sort of thing whilst we’re enjoying eating it, but the way that chocolate feels and melts in …

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Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape »

[7 Feb 2018 | ]

A week today, we will be excitedly preparing for the launch of the brand new Morphologi® 4 and Morphologi 4-ID! As we approach the next exciting chapter in Morphologi’s evolution, I’ve been looking back at just how far this instrument has come over the years.
Malvern Panalytical’s first foray into static morphological imaging was our acquisition of the Pharma Vision 830 in late 2003.  This system worked by using a linear actuator to automatically move the camera across the sample tray as it took digitized video images. At the time, it …

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Image Analysis, Meet the Experts, Morphologi, Particle shape, Particle size »

[28 Dec 2017 | ]

After a break of 4 years, it was great to get back to the Drug Delivery to the Lungs conference (DDL2017) in Edinburgh this year. After the snow and gales of previous years when I have visited it was rather quiet in terms of weather this year, but not in terms of content as this was varied and interesting. I caught up on some of the latest advances in inhaled device development targeting special populations, such as small children or critically ill patients. It was really exciting to see the …

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Chemical identification, Image Analysis, Meet the Experts, Morphologi, Particle shape, Raman spectroscopy »

[29 Sep 2017 | ]

I have just come back from presenting my talk ‘Application of Morphologically-Directed Raman Spectroscopy in deformulation and in vitro bioequivalence studies’ at the pharma focus session of Powtech 2017.
The talk indicated how there are still many drug products that have come of patent but do not yet have generic equivalents available and how there is a drive from the regulatory bodies to make health care more accessible and so they are producing many guidance documents to help address this.
I gave an overview of a proposed workflow for developing generic drug …

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Archimedes, Binding affinity and Kd, Chemical identification, Differential Scanning Calorimetry, Dynamic Light Scattering, Gel permeation chromatography, Image Analysis, Label-free analysis, MicroCal, Microcalorimetry, Morphologi, Nanoparticle Tracking Analysis, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Raman spectroscopy, Resonant mass measurement, Rheology, Size Exclusion Chromatography, Taylor Dispersion Analysis, Tech Talk, Viscosizer TD, Viscotek, Zetasizer »

[21 Sep 2017 | ]

I know this sounds like the beginning of a bad joke, but in this case, it was actually the beginning of the 2017 Colorado Protein Stability Conference, held in July at Beaver Run Resort in Breckenridge, Colorado. In attendance was a range of scientists and researchers from all over the world, with one common subject in mind: Protein Stability.

One of the highlights of this conference was the pre-conference workshop. This was a free workshop for all attendees of the conference, which was sponsored by Malvern Panalytical. The workshop included a range …

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Chemical identification, Image Analysis, Meet the Experts, Morphologi, Particle shape »

[7 Sep 2017 | ]

Standing at just under 3800 m tall with its distinctive symmetrical cone-shaped peak, the majestic Mount Fuji, or Fujisan (富士山) as it is known locally, is one of the most iconic symbols of Japan.
Therefore, it seemed only appropriate that whilst on secondment in Malvern’s Tokyo application lab, I should attempt to reach the summit of this famous volcano and, in something of a cliché, watch the sunrise from the highest peak in the Land of the Rising Sun.
There is only a short window each year in which one is permitted …

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Morphologi, Particle shape, Raman spectroscopy, Tech Talk »

[31 Aug 2017 | ]

GEN covers the role of MDRS in reducing the need for clinical bioequivalence endpoint studies
 
 
Raman spectroscopy and MDRS enable determination of the size and shape of specific components within a multi-component blend.
This article followed the recent approval of an abbreviated new drug application (ANDA) for a locally-acting mometasone furoate nasal spray, which provided the opportunity for the US Food and Drug Administration (FDA) to highlight the pivotal and pioneering role MDRS played.
MDRS enables determination of the size and shape of specific components within a multi-component blend. For the purposes of …

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Archimedes, Chemical identification, Label-free analysis, Malvern Panalytical Events, MicroCal, Microcalorimetry, Molecular size, Molecular structure, Molecular weight, Morphologi, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Protein Mobility, Viscosizer TD, Zeta potential, Zetasizer »

[16 May 2017 | ]

With Pre-Conference Workshop on Biophysical Characterization and Particle Analysis
 

Date: July 17th – 20th.
We at Malvern know that protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that researchers from all the relevant areas can join to discuss the critical issues in the field. The 2017 Colorado Protein Stability Conference provides a unique forum for this exchange of information. The topics to be covered include protein folding, dynamics and thermodynamic stability; amyloidosis and protein aggregation; and stability, formulation, analysis and processing …

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Français, Insitec, Laser Diffraction, Malvern Panalytical Events, Meet the Experts, Particle shape, Particle size »

[2 May 2017 | ]

Malvern organise des formations en collaboration avec la société SDTech Micro et SDTech Nano, son partenaire technique depuis 7 ans.

SDTech Micro, situé à Alès, est spécialisé dans l’analyse et le traitement à façon des poudres fines et ultrafines.
La semaine derniere, SDtech organisait les journees techniques avec Glatt et Malvern. Des présentations théoriques s’enchainerent avec des ateliers sur un granulateur Glatt en mode “granulation” le premier jour puis en mode “enrobage” le deuxième jour.

 

En parallèle une démonstration de broyage sur un microniseur à jet d’air contrôlé entièrement par un granulomètre laser …

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Malvern Panalytical Events, Particle shape, Particle size, Rheology »

[6 Oct 2016 | ]

Best practices for characterizing and manufacturing battery slurries and electrodes
The market for batteries is rapidly growing, and the increased demand for portable electronic devices, including mobile phones and laptops requires greater advances in battery technology in order to provide a light weight, long lasting and stable power source. Battery technology is also being pushed further in electric vehicle applications, which require even more lightweight, higher power and faster charging batteries.

Critical for the development and production of a battery is getting the right material composition and putting it together in such …

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Chemical identification, Image Analysis, Laser Diffraction, Malvern Panalytical Events, Mastersizer, Morphologi, Particle shape, Particle size, Raman spectroscopy »

[29 Jun 2016 | ]

Over the past week I’ve had a lot of fun working with Malvern’s team in China to deliver a series of seminars designed to help researchers engaged in pharmaceutical product development. These meetings focused on how Malvern’s material characterization systems can help those developing and manufacturing oral solid dose formulations. During the seminar series, we had the privilege of meeting with well over 200 customers, providing us with the chance to learn about the challenges they are facing in product development, as they seek to select APIs and excipients which …

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Chemical identification, Image Analysis, Laser Diffraction, Mastersizer, Meet the Experts, Morphologi, Particle shape, Particle size, Raman spectroscopy, Tech Talk »

[20 Jun 2016 | ]

Component-specific Particle Size
Follow that particle!

I’ve always thought it would be great to be the innocent driver in a movie chase scene who has to respond to the hero’s demand to ‘Follow that car’ as they try to keep tabs on the villain. I always imaged that this would unlock the silent racing driver within me, giving me the excuse to forget about speed limits and drive at the limits of my car’s performance. I’d also get the chance to practice my handbrake turns!
Although I have never been engaged in a …

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Chemical identification, Kinexus, Morphologi, Particle shape, Spraytec, Tech Talk »

[14 Jun 2016 | ]

MDRS Technology
Finally!  After what has felt like one of the wettest and longest winters in memory here in the UK, we’re now heading into the long, mellow days of midsummer.
But casting its miserable shadow over the barbecues, school holidays and paddling pools is the dreaded allergy season.  As one of the downsides of life in our “green and pleasant land”, during June we are hit hard by the combined impact of pollen from trees, grasses and weeds.
Many of us are now taking a daily antihistamine of some sort, and others …

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Particle shape, Particle size »

[25 Mar 2016 | ]

In the UK we are about to celebrate Easter, where we get the chance to spend a few days relaxing with family and friends and enjoying the start of spring. It is traditional at this time of year to give away chocolate Easter eggs, as a symbol of new life.
So, for me, the hunt is on for the perfect Easter egg for my family. As I do this, the questions I find myself asking are:

What size is it?
What shape is it?
What does it contain?

Interestingly these are precisely the same questions …

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Particle shape, Particle size »

[25 Nov 2015 | ]

Ever thought about measuring the size of a potato?  We’ll probably be consuming vast quantities of these in various forms (fries, roasted, mashed, even potato salad which signals summer in the US). Well, the humble potato is a good example of the philosophy of the most basic particle size question “What size is my particle?”. Do we buy our potatoes on the basis of number (I can understand this for large baking potatoes or the tiny new potatoes we used to see every year in my youth in England – now of …

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Mastersizer, Meet the Experts, Particle shape »

[8 Oct 2015 | ]

Hello once again from the Malvern development labs!
You may remember I wrote a blog last year about the Dispersion Index parameter on the Hydro Sight and how it can be used to supplement Mastersizer information on the dispersion state of your sample.  Well, in this blog I’m going to introduce you to another novel feature of the Hydro Sight:  automatic anomaly detection.  (There’s also a little game at the end that you can all play at home – and prizes are at stake….)
 
 
 
This feature is very useful for troubleshooting problems …

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