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Particle shape

Particle shape can have a significant impact upon the performance and process handling of many particulate materials.

Archimedes - Particle Metrology System, Chemical identification, Fluorescence Detection, Label-free analysis, Malvern Events, MicroCal, Microcalorimetry, Molecular size, Molecular structure, Molecular weight, Morphologi G3-ID, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Protein higher order structure, Protein Mobility, Viscosizer TD, Zeta potential, Zetasizer »

[16 May 2017 | ]

With Pre-Conference Workshop on Biophysical Characterization and Particle Analysis

Date: July 17th – 20th.
We at Malvern know that protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that researchers from all the relevant areas can join to discuss the critical issues in the field. The 2017 Colorado Protein Stability Conference provides a unique forum for this exchange of information. The topics to be covered include protein folding, dynamics and thermodynamic stability; amyloidosis and protein aggregation; and stability, formulation, analysis and processing …

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Français, Insitec, Laser Diffraction, Malvern Events, Meet the Experts, Particle shape, Particle size »

[2 May 2017 | ]

Malvern organise des formations en collaboration avec la société SDTech Micro et SDTech Nano, son partenaire technique depuis 7 ans.

SDTech Micro, situé à Alès, est spécialisé dans l’analyse et le traitement à façon des poudres fines et ultrafines.
La semaine derniere, SDtech organisait les journees techniques avec Glatt et Malvern. Des présentations théoriques s’enchainerent avec des ateliers sur un granulateur Glatt en mode “granulation” le premier jour puis en mode “enrobage” le deuxième jour.


En parallèle une démonstration de broyage sur un microniseur à jet d’air contrôlé entièrement par un granulomètre laser …

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Malvern Events, Particle shape, Particle size, Rheological and Viscosity »

[6 Oct 2016 | ]

Best practices for characterizing and manufacturing battery slurries and electrodes
The market for batteries is rapidly growing, and the increased demand for portable electronic devices, including mobile phones and laptops requires greater advances in battery technology in order to provide a light weight, long lasting and stable power source. Battery technology is also being pushed further in electric vehicle applications, which require even more lightweight, higher power and faster charging batteries.

Critical for the development and production of a battery is getting the right material composition and putting it together in such …

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Chemical identification, Image Analysis, Laser Diffraction, Malvern Events, Mastersizer, Morphologi G3-ID, Particle shape, Particle size, Raman spectroscopy »

[29 Jun 2016 | ]

Over the past week I’ve had a lot of fun working with Malvern’s team in China to deliver a series of seminars designed to help researchers engaged in pharmaceutical product development. These meetings focused on how Malvern’s material characterization systems can help those developing and manufacturing oral solid dose formulations. During the seminar series, we had the privilege of meeting with well over 200 customers, providing us with the chance to learn about the challenges they are facing in product development, as they seek to select APIs and excipients which …

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Chemical identification, Image Analysis, Laser Diffraction, Mastersizer, Meet the Experts, Morphologi G3-ID, Particle shape, Particle size, Raman spectroscopy, Tech Talk »

[20 Jun 2016 | ]

Component-specific Particle Size
Follow that particle!

I’ve always thought it would be great to be the innocent driver in a movie chase scene who has to respond to the hero’s demand to ‘Follow that car’ as they try to keep tabs on the villain. I always imaged that this would unlock the silent racing driver within me, giving me the excuse to forget about speed limits and drive at the limits of my car’s performance. I’d also get the chance to practice my handbrake turns!
Although I have never been engaged in a …

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Chemical identification, Kinexus, Morphologi G3-ID, Particle shape, Spraytec, Tech Talk »

[14 Jun 2016 | ]

MDRS Technology
Finally!  After what has felt like one of the wettest and longest winters in memory here in the UK, we’re now heading into the long, mellow days of midsummer.
But casting its miserable shadow over the barbecues, school holidays and paddling pools is the dreaded allergy season.  As one of the downsides of life in our “green and pleasant land”, during June we are hit hard by the combined impact of pollen from trees, grasses and weeds.
Many of us are now taking a daily antihistamine of some sort, and others …

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Particle shape, Particle size »

[25 Mar 2016 | ]

In the UK we are about to celebrate Easter, where we get the chance to spend a few days relaxing with family and friends and enjoying the start of spring. It is traditional at this time of year to give away chocolate Easter eggs, as a symbol of new life.
So, for me, the hunt is on for the perfect Easter egg for my family. As I do this, the questions I find myself asking are:

What size is it?
What shape is it?
What does it contain?

Interestingly these are precisely the same questions …

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Particle shape, Particle size »

[25 Nov 2015 | ]

Ever thought about measuring the size of a potato?  We’ll probably be consuming vast quantities of these in various forms (fries, roasted, mashed, even potato salad which signals summer in the US). Well, the humble potato is a good example of the philosophy of the most basic particle size question “What size is my particle?”. Do we buy our potatoes on the basis of number (I can understand this for large baking potatoes or the tiny new potatoes we used to see every year in my youth in England – now of …

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Mastersizer, Meet the Experts, Particle shape »

[8 Oct 2015 | ]

Hello once again from the Malvern development labs!
You may remember I wrote a blog last year about the Dispersion Index parameter on the Hydro Sight and how it can be used to supplement Mastersizer information on the dispersion state of your sample.  Well, in this blog I’m going to introduce you to another novel feature of the Hydro Sight:  automatic anomaly detection.  (There’s also a little game at the end that you can all play at home – and prizes are at stake….)
This feature is very useful for troubleshooting problems …

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Image Analysis, Morphologi G3-ID, Particle shape, Particle size, Raman spectroscopy, Tech Talk »

[11 Aug 2015 | ]

When working with a couple of our Morphologi G3-ID cement customers I have come to realize that cement is an incredibly complex product. Working with one of our customers in the cement industry we wrote an article, published last year in International Cement Review, discussing some of the challenges facing the cement industry and how the Morphologi G3-ID can help face these challenges.
Cements can contain a large number of components including any number of additives to adapt the cement behavior, the size and shape of any of these components can …

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Particle shape, Particle size, Tech Talk »

[10 Jul 2015 | ]

The longer you work at Malvern Instruments, the more likely you are to see anything and everything as something which has been optimized by material characterization in some form. As it’s the week of The Open at St Andrews, let’s take the golf course as an example. Surely particle science has no place here does it? Well it does, in fact, it has been deliberately designed to have a particularly perfect particle size.
The most obvious place to start, but the hardest to escape from, is the bunker. The particle size …

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Molecular size, Molecular structure, Molecular weight, Particle shape, Protein Mobility, Zetasizer »

[30 Jun 2015 | ]

The Zetasizer has some optional advanced protein features that you may not be aware of:
DLS Debye Plot: a dynamic Debye plot of the measured hydrodynamic size as a function of sample concentration to obtain the dynamic Virial coefficient (also known as kd, or interparticle interaction parameter)
Mixture Viscosity: estimates the viscosity of a mixture of dispersants of known viscosity, using the assumption that the total viscosity is a volume fraction weighted sum of the component viscosities. The mean viscosity is based on the volume fraction and the individual viscosities of the component …

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Laser Diffraction, Mastersizer, Particle shape, Particle size, Sysmex FPIA-3000, Tech Talk »

[14 May 2015 | ]

In this series of blogs I, and some of my colleagues, would like to share some of our experience in particle sizing for industrial applications. I thought we’d do this by going through an A to Z of industrial applications and as Aardvarks are too big for our instruments, we’ll start with A for abrasives.
To be an abrasive, a material needs to be harder than the material that you want remove or polish (unless you have got a very, very long time to wait – think glacial!). The original scale …

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Particle shape, Tech Talk, Zetasizer »

[21 Apr 2015 | ]

What laser is used in the Zetasizer Nano series? This question came to me via one of our Malvern account managers, so I thought a brief explanation could help clarify which laser and which detector is used in the systems.
Helium Neon HeNe lasers (λ=632.8nm) were the first commercial lasers, and they have superior beam qualities (for example in stability, mode, and coherence length).  Since they have been around for decades, they are also reliably durable. Traditionally the first light scattering experiments were conducted using various gas lasers and photo multiplier tubes PMTs …

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Customer experience, Mastersizer, Morphologi G3, Parsum, Particle shape, Particle size, Spatial Filter Velocimetry, Tech Talk »

[8 Apr 2015 | ]

Fluidized Bed Coating
Improving the fluidized bed coating process with PAT & AI
Leia este blog no Português
On the morning of February 25, 2015, a doctoral defense was performed by Carlos Alexandre Moreira da Silva, Master in Chemical Engineering from University State of Campinas (Unicamp), under Prof. Dr. Osvaldir Taranto Pereira’s supervision.
The thesis titled “Application of Process Analytical Technology and Artificial Intelligence to monitor and control a fluidized bed coating process” developed in Chemical Engineering Faculty at the State University of Campinas, set an innovation in the study of the key parameters involved …

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Customer experience, Parsum, Particle shape, Particle size, Português, Spatial Filter Velocimetry, Tech Talk »

[8 Apr 2015 | ]

Read this blog post in English
Na manhã do dia 25 de fevereiro de 2015, foi realizada a defesa de doutorado de Carlos Alexandre Moreira da Silva, Mestre em Engenharia Química pela Unicamp, sob a orientação do Prof. Dr. Osvaldir Pereira Taranto, Chefe de Gabinete Adjunto da Reitoria da Unicamp.
A tese “Aplicação de Tecnologias Analíticas de Processo e Inteligência Artificial para Monitoramento e Controle de Processo de Recobrimento de Partículas em Leito Fluidizado”, desenvolvida na Universidade Estadual de Campinas (Faculdade de Engenharia Química), configurou uma inovação no estudo dos parâmetros essenciais …

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Malvern Events, Particle shape, Particle size »

[26 Mar 2015 | ]

What an amazing time we had at Pittcon in New Orleans this year!  The folks who visited our booth were treated to not one, but two contests to enter for the chance to win Amazon gift cards.
First, we challenged people to guess the number of ‘particles’ in the jar – we are the particle characterization experts after all! OK, so they weren’t really particles… as we were in NOLA just after Mardi Gras, we filled a great big jar with shiny beads and asked people to guess how many were in there for a chance …

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Malvern Events, Meet the Experts, Morphologi G3-ID, Particle shape, Particle size, Raman spectroscopy »

[11 Mar 2015 | ]

Hoax bioterrorism powder attacks are well known in the USA. Once it is established that the powder is not a real threat, the search is on to establish who made the hoax threat, and the clues can be right there in the powder itself.  Often artificial sweeteners are used, and whilst bulk Raman analysis can confirm that a powder is dextrose, Morphologically Directed Raman Spectroscopy (MDRS) can help go a step further and identify the specific sweetening agent, and therefore the brand, which may help in the search for the …

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Laser Diffraction, Mastersizer, Meet the Experts, Particle shape, Particle size, Spraytec, Tech Talk »

[3 Dec 2014 | ]

I’ll be manning the Malvern stand at DDL25 – the 25th Drug Delivery to the Lungs conference – which is taking place in Edinburgh next week, starting on 10th December.  I’m a technical specialist for diffraction products at Malvern, so I know the Mastersizer and Spraytec instruments inside out.  My challenge to you is to bring along your dodgy data for me to diagnose!
Got problems with your MDI? No, not your metered dose inhalers, your Method Development Investigations!  Need help with your API? I’m talking about Awkward Peak Investigations, not …

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Chemical identification, Customer experience, Morphologi G3-ID, Particle shape, Raman spectroscopy, Tech Talk »

[27 Nov 2014 | ]

Hello!  A few months ago I blogged about my up and coming visit to Australia and I promised to let you know if I made it to the top of the Sydney Harbour bridge – I am not sure where the time as flown to since then but I thought it was about time I let you know how the trip went.
One of the reasons I headed down under was to give 12 seminars; 4 each in Melbourne, Sydney and Brisbane – the team at ATA Scientific did a great …

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