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Phase identification

The identification of major and minor single or multiple phases in an unknown sample is the main application of classical X-ray powder diffraction. A phase is a crystalline solid with a regular 3-dimensional arrangement of the atoms. The measured diffraction peak positions and intensities are like a fingerprint of a particular crystalline phase. Identification is accomplished by comparison of the measured pattern with the entries in reference databases using a search-match algorithm. This is also known as qualitative phase analysis.

Crystal Structure Determination, Empyrean, Phase identification, Phase quantification, Tech Talk, X-Ray Diffraction (XRD), X-Ray Scattering »

[24 May 2018 | ]

Detection of trace polymorphs, determination of amorphous content, and the study of the stability of active pharmaceutical ingredients (APIs) subjected to heat and humidity are some of the many applications where a modern powder X-ray diffraction (PXRD) system can add value to drug development.  Advances in beam conditioning and detector technology have led to greatly improved detection limits, resolution, and range of applications now possible. Today’s modern, laboratory-based PXRD instrumentation and advanced software can greatly assist pharmaceutical scientists in their quest to develop high quality, stable products and accelerate their …

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