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Zeta potential

The benefits of using zeta potential measurements to improve formulation stability and shelf life and reduce formulation time and cost.

Customer experience, Dynamic Light Scattering, Electrophoretic light scattering, Molecular size, Particle size, Zeta potential, Zetasizer »

[25 May 2017 | ]

A challenge to all new Zetasizers!
 
The Zetasizer is so simple to use that the majority of Zetasizer (user)s just “dive in” and find out how to operate the system.
By design it is (almost) indestructable, so what can go wrong? Not much – nevertheless, you might be able to get even more use and benefit from your system with a little preparation.
 
Free eLearning video – really!
If you are relatively new to the Zetasizer then take a look at our free eLearning introductory course. It was meant as a teaser for the …

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Archimedes - Particle Metrology System, Chemical identification, Fluorescence Detection, Label-free analysis, Malvern Events, MicroCal, Microcalorimetry, Molecular size, Molecular structure, Molecular weight, Morphologi G3-ID, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Protein higher order structure, Protein Mobility, Viscosizer TD, Zeta potential, Zetasizer »

[16 May 2017 | ]

With Pre-Conference Workshop on Biophysical Characterization and Particle Analysis
 

Date: July 17th – 20th.
We at Malvern know that protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that researchers from all the relevant areas can join to discuss the critical issues in the field. The 2017 Colorado Protein Stability Conference provides a unique forum for this exchange of information. The topics to be covered include protein folding, dynamics and thermodynamic stability; amyloidosis and protein aggregation; and stability, formulation, analysis and processing …

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Customer experience, Dynamic Light Scattering, Molecular size, Particle size, Zeta potential, Zetasizer »

[4 May 2017 | ]

3 stumbling blocks for Report Designer (Zetasizer) – the rule of two
The three most common holdups encountered in the report designer feature are listed here.
Not everyone delves into the depth of the Zetasizer software, but of those who do want to take advantage of the report customization features in the ‘report designer’ nearly everyone runs into at least one of these three common mistakes:

1. Folder locations – there are two!
The Zetasizer software is typically installed in a (hidden) Windows directory like  C:\Program Files\Malvern Instruments\Zetasizer Software and that’s good. However, if …

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Dynamic Light Scattering, Electrophoretic light scattering, Meet the Experts, Static Light Scattering, Zeta potential, Zetasizer »

[16 Mar 2017 | ]

Recently, I hosted a webinar which discussed what surface zeta potential is and how it can be measured. The webinar attracted huge interest and it was a pleasure to see so many people attending and asking some excellent questions. In fact, there were so many questions asked, that we ran out of time at the end of the webinar and had to answer many of them via e-mail. Some of these are listed below.
The webinar discussed the zeta potential of solid, planar surfaces (rather than colloidal dispersions or molecular solutions) …

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Français, Meet the Experts, Zeta potential, Zetasizer »

[13 Mar 2017 | ]

Les deuxièmes ateliers de l’IFTS (Institut de Filtration et des Techniques Séparatives) auront lieu les 15 et 16 mars à Foulayronnes (près d’Agen).
Cette année, ces ateliers seront dédiés à la caractérisation des boues et suspensions.
Le mercredi 15 mars, de 15H15 à 15H30, Michel Terray et Alain Blasco présenteront le Zetasizer WT, appareil pour la mesure en ligne du potentiel zêta lors d’une conférence intitulée “Process control of water treatment and filtration by zeta potential measurement” contenant :

Intérêt du potentiel zêta dans le suivi de floculation
Exemple d’application chez Wemlinger et Severn Trent Water
Retour d’expérience basé sur …

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Binding affinity and Kd, Differential Scanning Calorimetry, Dynamic Light Scattering, Français, Gel permeation chromatography, Image Analysis, Isothermal Titration Calorimetry, Laser Diffraction, Meet the Experts, Molecular size, Nanoparticle Tracking Analysis, Particle concentration, Particle size, Rheological and Viscosity, Rheometry - Rotational, Size Exclusion Chromatography, Static Light Scattering, Zeta potential »

[21 Feb 2017 | ]

Afin de vous apporter un support concret pour utiliser votre système de façon optimale, finaliser vos bonnes pratiques de laboratoire et répondre à vos besoins spécifiques, Malvern organise des formations sur site ou en sessions dans nos 3 agences françaises (Orsay, Lyon et Toulouse).
Voici les dates de toutes les sessions programmées pour 2017 :
CARACTERISATION DES PARTICULES PAR DIFFRACTION LASER
Objectifs : Perfectionner les méthodes de caractérisation des particules en voie sèche et liquide, définir les bonnes pratiques de laboratoire et s’adapter aux besoins spécifiques de chaque installation. Comprendre le principe physique …

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Meet the Experts, Molecular weight, OMNISEC, Particle size, Tech Talk, Zeta potential, Zetasizer »

[30 Jan 2017 | ]

Malvern Instruments takes part at the 8th International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules (SCM-8) at Rhone Events & Congrescenter. The main interest of the conference is the separation and characterization of large molecules. The target audience includes specialists from analytical chemistry, polymer science, and life-science communities.
Malvern is a sponsor of the conference so keep an eye out for us at our booth. In addition, I will give a talk on Thursday February, 2nd about ‘Combining Multi-Detector GPC Measurements with Ultra-High Performance GPC Separations’. The …

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Dynamic Light Scattering, Gel permeation chromatography, Malvern Events, Meet the Experts, Nanoparticle Tracking Analysis, Size Exclusion Chromatography, Zeta potential »

[26 Jan 2017 | ]

We will be attending Pittcon 2017 in Chicago, Illinois March 5th – 9th and once again we are pleased to feature a number of our recognized characterization experts who will be presenting a variety of short courses throughout the week.
Time is running out, so don’t miss out on the early bird deadline for discounted admission which ends on February 18th.
Below is a listing of our available short course offerings.
We look forward to seeing you in Chicago at one of our short courses and our Booth #2416.
Sunday, March 5, 2017 – 8:30 AM
Light Scattering …

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Customer experience, Dynamic Light Scattering, Electrophoretic light scattering, Molecular size, Molecular weight, Particle size, Zeta potential, Zetasizer »

[20 Oct 2016 | ]

How can I save paper and print a Zetasizer report as a PDF?
 
Why print?
The Zetasizer software includes several popular report options. The most frequently used of these is probably the Intensity PSD (M), which gives a compact overview of the results. It lists the z-average and up to three peaks by intensity with their respective mean size, the area under the peak in % intensity and the standard deviation of the peak. In addition, several relevant sample identifiers and measurement conditions, like the sample name,  file name, refractive index of …

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Customer experience, Meet the Experts, Zeta potential, Zetasizer »

[13 Oct 2016 | ]

Water Treatment
The 7th International Conference and exhibition on Water Wastewater and Environmental Monitoring (WWEM) will take place at Telford, England on 2-3 November 2016.
We are giving a workshop on Thursday 3rd at 11:00 (in room 7).
This is “A brief introduction to zeta potential and sizing techniques in the water industry” and will mainly be focused on zeta potential which is gaining popularity as a monitor of particle instability to optimize the addition of expensive treatment chemicals, ultimately saving money.
Seasonal and geographical variation means the amount of chemical coagulant that needs …

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Dynamic Light Scattering, Electrophoretic light scattering, Meet the Experts, Particle size, Protein Aggregation, Zeta potential, Zetasizer »

[11 Oct 2016 | ]

Adjuvants for vaccination – How size and zeta may be relevant
 
What is an adjuvant?
Adjuvants are substances which are added to medicines to trigger and enhance an immune response to an antigen. In the USA, the most commonly-used adjuvant is alum, and many vaccines in use today contain some aluminum components to help the vaccine work better. While the exact mechanisms of how adjuvants work is unclear to some extent, a typical adjuvant component is much larger than the antigen or antibody itself, often around 100 nm in radius.
In a paper entitled …

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Electrophoretic light scattering, Tech Talk, Zeta potential, Zetasizer »

[14 Jul 2016 | ]

Every once in a while, we get questions about older light scattering systems which predate the  Zetasizer Nano series. While it is great to hear that these are still in operation, it can also present us with some challenges.  For example, if the system or accessory is no longer in production, and this has been the case for a number of years, are we still able to support it?  On the plus side, we have lots of employees that have stayed with Malvern for more than a decade – some …

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Customer experience, Zeta potential »

[1 Jun 2016 | ]

Fort McMurray is a small town in Canada caught in the grip of a natural disaster – a large wildfire burning southwest of the city. More than 100,000 residents of the city and the surrounding area were evacuated. As fire swept towards the city the largest wildfire evacuation in Canadian history was underway.
In the aftermath of events in Fort McMurray an urgent email from Mark Kitching, our Regional Sales Manager for Malvern Instruments Canada was received.
“How quickly can we get a Zeta WT unit out to Canada? – This is a disaster …

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Meet the Experts, Zeta potential, Zetasizer »

[5 May 2016 | ]

Water treatment – a better way than jar testing?
Water is at the foundation of life. Thus for humans H2O is of critical importance and most directly so for drinking water. In order to prepare water for safe consumption, water treatment procedures have been developed and improved to provide a reliable source of healthy drinking water through the use of chemicals for coagulation and flocculation. Zeta potential measurements can assist this process and help realize potential cost savings on chemical usage and sludge disposal costs.
 
 
The water treatment process – traditional jar tests
Water treatment …

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Malvern Events, Meet the Experts, Particle size, Zeta potential »

[28 Jan 2016 | ]

If you are planning to attend Pittcon 2016 in Atlanta, Georgia we hope you will join us at one of our short courses. Our recognized characterization experts will be presenting a variety of topics throughout the week.
Don’t delay – The early bird deadline for discounted admission ends on February 12.
Below is a listing of our available short course offerings.
We look forward to seeing you in Atlanta! Booth 3349
Monday, March 7, 2016
Fundamentals of Particle Size Analysis with an Emphasis on Light Scattering Techniques – Alan Rawle & Ulf Nobbmann
Wednesday, March 9, 2016
Separations: Fundamentals of Advanced Gel …

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Customer experience, Zeta potential, Zetasizer »

[14 Jan 2016 | ]

We are delighted to let you know that one of our new products, the Zetasizer WT, a dedicated on-line zeta potential analyzer for the Water Treatment industry won an Innovation award recently.
The event was held in November 2015 at the headquarters of Severn Trent Water in Coventry, UK, by the CIWEM (Certified Institute of Water and Environmental Management) and showcased ten new products available to the water treatment industry.
A show area was set up where representatives from the water industry could view and ask questions regarding the products on show and get a better understanding of their purpose and benefits. Malvern …

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Electrophoretic light scattering, Nanosight, Protein Mobility, Tech Talk, Zeta potential, Zetasizer »

[24 Nov 2015 | ]

How to perform zeta potential measurement with the diffusion barrier method?

The diffusion barrier method is particularly suitable for low sample volumes and high ionic strength buffers. A “plug” of the sample is carefully injected into the folded capillary cells which is filled with just the buffer (The buffer has to be the same buffer that the protein is prepared in, same conductivity, same pH, same additives, in order to match the sample and the diffusion barrier as closely as possible). In this setup, primarily the zeta potential is of interest, however …

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Malvern Events, Meet the Experts, Particle size, Zeta potential »

[10 Nov 2015 | ]

 
 
 
Malvern will be attending Pittcon 2016 in Atlanta, Georgia and once again we are pleased to feature a number of our recognized characterization experts who will be presenting a variety of short courses throughout the week.
Below is a listing of our available short course offerings. Register now to receive a discounted rate on your registration.
We look forward to seeing you in Atlanta! Booth 3349
Monday, March 7, 2016
#16 – Fundamentals of Particle Size Analysis with an Emphasis on Light Scattering Techniques – Alan Rawle & Ulf Nobbmann
A full 1-day course that will bring newcomers to the particle sizing …

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Customer experience, Particle size, Zeta potential, Zetasizer »

[5 Nov 2015 | ]

Congratulations to Professor Kathryn Whitehead at CMU!

 
We were delighted to hear that Kathryn Whitehead at Carnegie Mellon University was selected as one of this year’s  “Brilliant Ten” by Popular Science.  She was chosen for her exciting research on nanoparticle drug delivery vehicles involving short (also known as small) interfering ribonucleic acids (siRNAs).
 
 
 
 
Cellular uptake of these delivery agents is affected by their size: in one of Prof. Whitehead’s recent publications ‘Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model‘, nanoparticles with diameters of 110 …

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Meet the Experts, Particle size, Rheological and Viscosity, Zeta potential »

[29 Sep 2015 | ]

When you see the words “perfect packing” are you thinking of getting ready for that vacation and neatly folding your swimming costume and other clothes into your suitcase?  Or are you thinking of the worst-suitcase scenario when you’re packing after your vacation and trying to get that didgeridoo, boomerang,  and other assorted odd-sized souvenirs into that same suitcase, finding you have a problem, and having to buy another suitcase or ship the odd-shaped ornaments by other routes?
 
I won’t bore you with the story of trying to be smart, shipping my …

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