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Morphological imaging is fast becoming an essential technology in the laboratory toolkit for particle characterization. The Morphologi 4 is a fully automated static image analysis system which provides a complete detailed description of the morphological properties of particulate materials. The Morphologi 4-ID combines the same automated static image analysis with Raman spectroscopy in a single, integrated platform, providing component-specific morphological descriptions of chemical species within a blend.

Chemical identification, Image Analysis, Inside Malvern Panalytical, Morphologi, Particle shape »

[27 Feb 2018 | ]

What a wonderful boost we had to the February 14th launch of the new Morphologi 4 and Morphologi 4-ID when we found out that these systems were winners of an iF (Industrie Forum) Design 2018 award!  As the Project Manager responsible for Visual Brand Language on the Morphologi 4 range, I work closely with the design teams both here at Malvern Panalytical, and also at DCA Design, the agency which helped bring our vision for the instruments to life!
So, what are some of the design changes we implemented in the …

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Aeris, ASD, Claisse, Epsilon, Malvern Panalytical Events, Meet the Experts, Morphologi, OMNISEC, Zetasizer »

[20 Feb 2018 | ]

This year will be the 19th Pittcon in a row that I have attended (there should be an award for that, right?). Actually, Malvern Panalytical did receive an award from Pittcon 11 years ago for our then 50th anniversary of attending the conference.  If you still have not made it to this annual gathering of the latest in laboratory equipment, educational courses and technical presentations galore, here are some reasons to consider heading to Orlando on February 26 (or Philadelphia in 2019):
1 – You can see the latest in analytical …

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Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape »

[14 Feb 2018 | ]

東京へ ようこそ!  Welcome to Tokyo!  I’m very excited to return to Japan with the launch of the new Morphologi 4 range here at Tokyo Big Sight.  We’re at Nanotech 2018, and the additive manufacturing technology exhibition running concurrently – but more on that later.
My return to Japan with the Morphologi 4 also marks the completion of a personal journey, which started almost three years ago when I seconded to our Tokyo office to learn more about the customer applications of the previous Morphologi platform, the G3. (In fact, if you tune in to …

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Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape »

[13 Feb 2018 | ]

As I find myself surrounded by snow in Paris – the city of love – I’ve received news from my colleague, Sarennah Longworth-Cook, who has just been measuring chocolate on the new Morphologi 4 using the new Sharp Edge measurement mode.  How apt, since we’ll be launching the new Morphologi 4 range on Valentine’s Day!
So, what can Morphologi 4 tell us about our delicious chocolatey treats?

I know we don’t all think about this sort of thing whilst we’re enjoying eating it, but the way that chocolate feels and melts in …

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Chemical identification, Image Analysis, Malvern Panalytical Events, Morphologi, Particle shape »

[7 Feb 2018 | ]

A week today, we will be excitedly preparing for the launch of the brand new Morphologi® 4 and Morphologi 4-ID! As we approach the next exciting chapter in Morphologi’s evolution, I’ve been looking back at just how far this instrument has come over the years.
Malvern Panalytical’s first foray into static morphological imaging was our acquisition of the Pharma Vision 830 in late 2003.  This system worked by using a linear actuator to automatically move the camera across the sample tray as it took digitized video images. At the time, it …

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Image Analysis, Meet the Experts, Morphologi, Particle shape, Particle size »

[28 Dec 2017 | ]

After a break of 4 years, it was great to get back to the Drug Delivery to the Lungs conference (DDL2017) in Edinburgh this year. After the snow and gales of previous years when I have visited it was rather quiet in terms of weather this year, but not in terms of content as this was varied and interesting. I caught up on some of the latest advances in inhaled device development targeting special populations, such as small children or critically ill patients. It was really exciting to see the …

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Chemical identification, Image Analysis, Meet the Experts, Morphologi, Particle shape, Raman spectroscopy »

[29 Sep 2017 | ]

I have just come back from presenting my talk ‘Application of Morphologically-Directed Raman Spectroscopy in deformulation and in vitro bioequivalence studies’ at the pharma focus session of Powtech 2017.
The talk indicated how there are still many drug products that have come of patent but do not yet have generic equivalents available and how there is a drive from the regulatory bodies to make health care more accessible and so they are producing many guidance documents to help address this.
I gave an overview of a proposed workflow for developing generic drug …

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Archimedes, Binding affinity and Kd, Chemical identification, Differential Scanning Calorimetry, Dynamic Light Scattering, Gel permeation chromatography, Image Analysis, Label-free analysis, MicroCal, Microcalorimetry, Morphologi, Nanoparticle Tracking Analysis, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Raman spectroscopy, Resonant mass measurement, Rheology, Size Exclusion Chromatography, Taylor Dispersion Analysis, Tech Talk, Viscosizer TD, Viscotek, Zetasizer »

[21 Sep 2017 | ]

I know this sounds like the beginning of a bad joke, but in this case, it was actually the beginning of the 2017 Colorado Protein Stability Conference, held in July at Beaver Run Resort in Breckenridge, Colorado. In attendance was a range of scientists and researchers from all over the world, with one common subject in mind: Protein Stability.

One of the highlights of this conference was the pre-conference workshop. This was a free workshop for all attendees of the conference, which was sponsored by Malvern Panalytical. The workshop included a range …

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Deutsch, Insitec, Kinexus, Malvern Panalytical Events, Mastersizer, Morphologi, Nanosight, Zetasizer »

[14 Sep 2017 | ]


Read this blog in English
Die POWTECH ist weltweit die unangefochtene Nummer eins für Pulver-, Granulat- und Schüttguttechnologien. Sie spiegelt den aktuellen Stand der mechanischen Verfahrenstechnik und Analytik wider – und gibt damit einen einzigartigen Überblick für eine Vielzahl an Branchen. Seien Sie unser Gast und entdecken Sie auf der Leitmesse POWTECH 2017 vom 26.-28. September in Nürnberg am Malvern Panalytical Stand 1-314 alles rund um die Analytik von Pulvern, Schüttgut, Nanopartikeln und Dispersionen: Halten Sie bei uns einen Moment inne und erleben Sie gezielte Infos für Ihre Materialanalyse!
Fordern Sie Ihre …

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Insitec, Kinexus, Malvern Panalytical Events, Mastersizer, Morphologi, Nanosight, Zetasizer »

[14 Sep 2017 | ]

Diesen Eintrag auf Deutsch lesen
POWTECH is the undisputed number one meeting for powder, granule and bulk solids technologies, worldwide. It provides a showcase for cutting edge technologies and instrumentation relevant to a huge range of industries: from glass, building materials and paper, to pharmaceuticals, chemicals, and food.
Be our guest from 26-28 September in Nuremberg, Germany! Come and chat to the experts from Malvern Panalytical in Hall 1, at Stand 314.
Request your free admission ticket for Powtech 2017…..

…..and when the lights go down on the exhibition, head over to our Exclusive After-Hours Malvern Panalytical Powtech Party!  
Join …

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Chemical identification, Image Analysis, Meet the Experts, Morphologi, Particle shape »

[7 Sep 2017 | ]

Standing at just under 3800 m tall with its distinctive symmetrical cone-shaped peak, the majestic Mount Fuji, or Fujisan (富士山) as it is known locally, is one of the most iconic symbols of Japan.
Therefore, it seemed only appropriate that whilst on secondment in Malvern’s Tokyo application lab, I should attempt to reach the summit of this famous volcano and, in something of a cliché, watch the sunrise from the highest peak in the Land of the Rising Sun.
There is only a short window each year in which one is permitted …

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Morphologi, Particle shape, Raman spectroscopy, Tech Talk »

[31 Aug 2017 | ]

GEN covers the role of MDRS in reducing the need for clinical bioequivalence endpoint studies
Raman spectroscopy and MDRS enable determination of the size and shape of specific components within a multi-component blend.
This article followed the recent approval of an abbreviated new drug application (ANDA) for a locally-acting mometasone furoate nasal spray, which provided the opportunity for the US Food and Drug Administration (FDA) to highlight the pivotal and pioneering role MDRS played.
MDRS enables determination of the size and shape of specific components within a multi-component blend. For the purposes of …

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Chemical identification, Image Analysis, Morphologi »

[25 Jul 2017 | ]

Why is it that structures built in Roman times have resisted the elements for thousands of years when more modern structures have suffered?
This was a question posed in a recent BBC news story ‘Scientists explain ancient Rome’s long-lasting concrete’ that caught my eye since we have pondered the question here at Malvern before as you can see in this application note “Component Characterization of Cements” where the Morphologi G3-ID was used to study and compare the composition of different cements.

How is the concrete made?
Ancient structures are built using concrete made from …

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Archimedes, Customer experience, Differential Scanning Calorimetry, Gel permeation chromatography, Image Analysis, MicroCal, Morphologi, Nanoparticle Tracking Analysis, Nanosight, Particle size, Protein Aggregation, Raman spectroscopy, Resonant mass measurement, Viscotek »

[1 Jun 2017 | ]

Our key driver at Malvern Instruments is to create technologies that make a difference or solve a problem, and working hand-in-hand with our customers enables us to make sure that’s exactly what’s happening, out in the field.  We place a high value on our collaborations and partnerships with customers from a wide range of industries and organizations across the globe and love to see how our systems are being used in real-world scenarios.  This gives us vital feedback on what we’re doing well, and also any tweaks we need to make in order to optimize …

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Archimedes, Chemical identification, Label-free analysis, Malvern Panalytical Events, MicroCal, Microcalorimetry, Molecular size, Molecular structure, Molecular weight, Morphologi, Nanosight, Particle concentration, Particle shape, Particle size, Protein Aggregation, Protein Mobility, Viscosizer TD, Zeta potential, Zetasizer »

[16 May 2017 | ]

With Pre-Conference Workshop on Biophysical Characterization and Particle Analysis

Date: July 17th – 20th.
We at Malvern know that protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that researchers from all the relevant areas can join to discuss the critical issues in the field. The 2017 Colorado Protein Stability Conference provides a unique forum for this exchange of information. The topics to be covered include protein folding, dynamics and thermodynamic stability; amyloidosis and protein aggregation; and stability, formulation, analysis and processing …

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Image Analysis, Laser Diffraction, Mastersizer, Morphologi, Tech Talk »

[13 Apr 2017 | ]

The prevalence of chocolate eggs and chocolate bunnies in the supermarkets here in the UK can only signal one thing: Easter is upon us.  With the emergence of daffodils, buds appearing on trees, lambs frolicking in the fields and warmth seeping back into the northern hemisphere, the cold winter months are over.  Of course, it is not just in the western world that the arrival of spring, new life and new beginnings are celebrated.
In Japan, a country I had the pleasure of living in for a year and a half …

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Customer experience, Insitec, Kinexus, Mastersizer, Morphologi, Tech Talk »

[30 Mar 2017 | ]

The recently announced merger of Malvern Instruments and PANalytical could not be better timed from the Cement industry’s perspective. Both companies are market leaders in their respective technology fields – Malvern in particle characterization and PANalytical in elemental and mineralogical analysis – and both having strong teams of application experts with a lot of experience in cement production and characterization.
The synergy between the teams and product offerings was described in a recent webinar by Harald van Weeren of PANalytical and myself. The live event was attended by over one hundred participants and …

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Customer experience, Morphologi »

[10 Jan 2017 | ]

At Malvern, we love hearing stories from our customers about how they use our technologies to help them better understand and control their products. From time to time we are going to share some of these stories in a feature we have entitled “Customer Spotlight”.
Our very first Customer Spotlight is from Amber Fradkin of the Particle Characterization Core Facility at KBI Biopharma in Boulder, CO. Amber received her Ph.D. in Chemical Engineering within the Pharmaceutical Biotechnology Program, with a specialization in the field of immunogenicity of therapeutic protein aggregates, at the University …

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Mastersizer, Morphologi »

[24 Nov 2016 | ]

Additive manufacturing, also commonly referred to as 3D printing is the process of building a three dimensional structure or component from the ground up, usually layer by layer. There are seven main categories of additive manufacturing processes, as defined by the ASTM Committee F42 on Additive Manufacturing Technologies. These include:

Powder Bed Fusion
Vat Polymerisation (Stereolithography)
Material Extrusion (Fused Deposition Modeling)
Material Jetting
Binder Jetting
Sheet Lamination

Powder bed fusion is an Additive Manufacturing process in which a powder layer is deposited on a building platform and a laser or electron beam used to selectively melt or fuse …

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Chemical identification, Image Analysis, Laser Diffraction, Malvern Panalytical Events, Mastersizer, Morphologi, Particle shape, Particle size, Raman spectroscopy »

[29 Jun 2016 | ]

Over the past week I’ve had a lot of fun working with Malvern’s team in China to deliver a series of seminars designed to help researchers engaged in pharmaceutical product development. These meetings focused on how Malvern’s material characterization systems can help those developing and manufacturing oral solid dose formulations. During the seminar series, we had the privilege of meeting with well over 200 customers, providing us with the chance to learn about the challenges they are facing in product development, as they seek to select APIs and excipients which …

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