The Sysmex FPIA 3000 is a fully automated dynamic flow particle imaging instrument for the rapid and reliable measurement of the shape and size of particles in suspension.
In this series of blogs I, and some of my colleagues, would like to share some of our experience in particle sizing for industrial applications. I thought we’d do this by going through an A to Z of industrial applications and as Aardvarks are too big for our instruments, we’ll start with A for abrasives.
To be an abrasive, a material needs to be harder than the material that you want remove or polish (unless you have got a very, very long time to wait – think glacial!). The original scale …
Archimedes - Particle Metrology System, Dynamic Light Scattering, Particle size, Resonant mass measurement, Sysmex FPIA-3000, Tech Talk, Zetasizer »
Recently this question was posed where a current dynamic light scattering (DLS) user inquired about detecting large but subvisible particles in a formulation:
“I have been looking at solutions from prefilled syringes which appear in flow microscopy to have significant levels of oligo-micron-sized silicone oil droplets. I don’t see any indication of these in my DLS measurements.”
With specifications for DLS systems like the Zetasizer from sub nanometer to several microns the initial concern is not unreasonable. However, on closer look the situation is not so apparent. The silicone oil droplets are …
Image Analysis, Morphologi G3, Sysmex FPIA-3000, Tech Talk »
After the last Imaging Masterclass on good experimental practice I thought I would share my top tips for sample preparation, based on my own experience. You can view the recording of the webinar here.
Get to know your sample!
The first thing I would advise anyone to do is to look at their sample. Take a dry powder – by tumbling a pot of sample you can assess how cohesive or how sticky a sample is. Small particles, smaller than 10 microns or so can be very cohesive due to high surface energy …
Dynamic Light Scattering, Electrophoretic light scattering, Image Analysis, Insitec, Laser Diffraction, Mastersizer, Morphologi G3, Parsum, Particle shape, Particle size, Rheological and Viscosity, Spatial Filter Velocimetry, Spraytec, Sysmex FPIA-3000, Tech Talk, Zeta potential, Zetasizer »
Particle Characterization Explained
There is a wide range of commercially available particle characterization techniques that can be used to measure particulate samples. Each has its relative strengths and limitations and there is no universally applicable technique for all samples and all situations.
Which particle characterization techniques do I need?
A number of criteria must be considered when deciding which particle characterization techniques you need:
• which particle properties are important to me?
• what particle size range do I want to work over?
• are my samples polydisperse i.e. do I need a wide dynamic range?
For many particle characterization applications, a particle size distribution provides adequate information about the sample. However, for some applications particle shape can provide more appropriate or complementary information. There are three main categories where this is relevant:
Single particles or agglomerates?
Many particle sizing methods require complete dispersion of any agglomerates in the sample in order to make an appropriate measurement. Being able to view individual images in the dispersion and analyze them in terms of their outline shape allows the user to determine whether or not agglomerates are present and the …
Many customers are not as familiar with automated imaging as a particle characterization technique. Here are three good reasons why you might want to consider automated imaging in addition to your more established techniques such as laser diffraction or microscopy.
Better understanding of particle properties
Automated imaging can provide data on particle size, shape, transparency and chemical identity in one measurement. In contrast to ensemble-based techniques such as laser diffraction, each individual particle in the sample is measured one-by-one, providing high resolution detailed information. This is often used to complement data from …
Particle shape, Particle size, Sysmex FPIA-3000 »
Receiving my household fuel bills, as I do with monotonous regularity, tends to focus my mind both on energy conservation and the cost of energy generation. Of course, this line of thinking quickly extends into the realms of professional interest as well and increasingly we see one of our particle characterization systems being used in a process that helps manage costs in the manufacture of photovoltaic (PV) cells.
Manufacturing PV solar cells
Photovoltaic (PV) solar cells, which convert light energy directly into electricity, are fabricated from a polysilicon ingot. This is turned …
According to an industry expert quoted on NewEnergyWorldNetwork the cost of lithium-ion batteries will drop by nearly a third within the next four years and may be halved by 2020. Vital to green technologies such as clean energy storage and electric vehicle applications, this reduction in cost will be a result of more efficient charging mechanisms and an increase in battery lifetimes.
The ability to measure, predict and control properties that extend battery life is therefore extremely important to this greener future.
More efficient charging mechanisms
Currently, manufacturers routinely employ carbon or graphite …
Corporate, Sysmex FPIA-3000 »
In October last year industrial sales and support activities for Malvern and Sysmex Corporation industrial particle characterization systems transferred to Malvern Japan and I would like to take this opportunity to extend my personal gratitude to the whole Sysmex team, for their hard work towards making this exchange of responsibilities run so smoothly. The entire process was a testament to their corporate philosophy to demonstrate both individual competence and unsurpassed teamwork with passion and flexibility.
Words from the President and CEO of Sysmex Corporation
During the transfer ceremony on 1 October, Hisashi …