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Laser Diffraction

Laser diffraction is a widely used particle sizing technique for materials ranging from hundreds of nanometers up to several millimeters in size.

Laser Diffraction, Raman spectroscopy, X-Ray Diffraction (XRD), X-Ray Fluorescence (XRF) »

[14 Sep 2018 | ]

Physical characterization of pharmaceutical drugs is an essential part of drug formulation to ensure efficacy, stability, and safety. Malvern Panalytical is pleased to offer two upcoming complimentary seminars in the US for advanced characterization technologies for improving small molecule and biological drug formulation outcomes.
Our seminars will focus on numerous concerns and technologies used in the physical characterization of drug formulations, both small molecule and biomolecule. Topics include:

Recent advances in powder X-ray diffraction (PXRD) for pharma
X-ray fluorescence (XRF) – the fast and easy alternative technique for USP 232
Resolve analytical challenges in …

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Kinexus, Laser Diffraction, Mastersizer, Particle size, Rheology, Rheometry »

[20 Jun 2018 | ]

Here at Malvern Panalytical, we seem to enjoy testing the rheological properties of drinks, particularly those of the alcoholic variety! John Duffy and Steve Carrington looked into the differences between traditional ales and they explored the properties of Guinness. Any excuse to go down the pub…!
Therefore, it was probably about time to explore the healthier option on the drinks menu, and an ideal hangover cure – smoothies. Additionally, this was a perfect opportunity to demonstrate our latest dispersion geometry using John’s loyal drinking partner – the Kinexus rheometer!
We decided to run …

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Insitec, Laser Diffraction, Mastersizer, Particle size, Tech Talk »

[17 Apr 2018 | ]

What is IIoT?
We now live in a world where there is an increasing reliance on the internet, not only for streaming movies or sending e-mails but for controlling a multitude of devices from domestic appliances to smart cars. The internet of things has also been embraced by the manufacturing industry, a paradigm known as the IIoT (Industrial Internet of Things) – when separate manufacturing units begin to function as one – and where the cloud is becoming the preferred way to store and share data.
Data has now become the lifeblood …

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Aeris, ASD, Epsilon, Laser Diffraction, Malvern Panalytical Events, Mastersizer, Near-InfraRed spectroscopy (NIR), Particle size, TerraSpec, X-Ray Diffraction (XRD), X-Ray Fluorescence (XRF) »

[22 Feb 2018 | ]

Malvern Panalytical will be in Minnesota, United States at the SME Annual Conference & Expo from February 25-28th!
SME is the Society for Mining, Metallurgy & Exploration Inc. This event gathers together the mining and mineral community, comprised of engineers, geologists, metallurgists, educators, students and researchers. The society advances the worldwide mining and underground construction community through information exchange and professional development.

ASD TerraSpec® Halo
We invite you to come discover the product lines of Malvern Panalytical and what we can do for your mining and mineral needs. Find the following instruments in our …

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Dynamic Light Scattering, Gel permeation chromatography, Kinexus, Laser Diffraction, Malvern Panalytical Events, Meet the Experts, Molecular weight, Nanoparticle Tracking Analysis, Nanosight, OMNISEC, Particle concentration, Particle size, Rheology, Rheometry, Tech Talk, Viscotek, Zeta potential, Zetasizer »

[30 Jan 2018 | ]

We will be attending Pittcon 2018 in Orlando, Florida Feb 26th – Mar 1st and once again we are pleased to feature a number of our recognized characterization experts who will be presenting a variety of short courses throughout the week.
Time is running out, so don’t miss out on the early bird deadline for discounted admission which ends on February 5th.
Below is a listing of our available short course offerings.
We look forward to seeing you in Orlando at one of our short courses and our Booths #2118 & #2119.
Monday, February 26th
Fundamentals of Particle …

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Dynamic Light Scattering, Kinexus, Laser Diffraction, Mastersizer, Nanoparticle Tracking Analysis, Nanosight, Rheometry, Size Exclusion Chromatography, Tech Talk, X-Ray Diffraction (XRD), Zetasizer »

[5 Dec 2017 | ]

It was my great pleasure to present as part of the Worcestershire Innovation Network at their WINN Wednesday event on the 22nd of November, showcasing the best in innovation across Worcestershire.
This included a local company which makes artificial kneecaps and hips, an insight into the building of genomics studies of patients with rare diseases and cancers, an update on the appeal to get a state-of-the-art surgical robot for removal of prostate tumors (reducing discomfort, scarring and hospital stay post-operation). Jess Antley, head of WINN, also gave an update on a new shared space/collaboration …

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Français, Insitec, Laser Diffraction, Malvern Panalytical Events, Meet the Experts, Particle size »

[15 Nov 2017 | ]

Le Salon des technologies des solides et liquides en vrac

Nous serons présents sur le Salon Vrac Tech du 28 au 30 novembre 2017 – Hall C – Stand A19.
Vous pourrez découvrir nos granulomètres laser pour contrôler vos procédés de fabrication de poudres jusqu’à 1 mm et des sondes pour mesurer des granulés en ligne jusqu’à 6 mm. En effet, le contrôle des procédés de broyage intéresse et concerne de plus en plus d’usines de l’industrie alimentaire.
Rejoignez nous et demandez votre badge!
Informations pratiques :
Parc des Expositions du Mans
1, Avenue du Parc des Expositions
72100 Le Mans
Coordonnées …

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Insitec, Laser Diffraction, Malvern Panalytical Events, Particle size »

[19 Oct 2017 | ]

Downstream in-line monitoring for better processes and products
Every second is critical towards rectifying a plant upset or ensuring efficient plant management. What if you could incorporate in-line analysis for your dry and liquid products?
Companies that introduced in-line particle size analysis at the milling stage noticed significantly less over-milling. Hence seeing as much as a 2% increase in plant throughput. In-line elemental analysis allows petrochemical companies to closely monitor Fe, Ni, V which destroy expensive catalysts.
Why incorporate in-line analysis?

Real-time monitoring of your batches
Make immediate corrections to poor batches
Prevent wastage
Improve your manufacturing …

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Laser Diffraction, Malvern Panalytical Events, Mastersizer »

[10 Oct 2017 | ]

Consumers increasingly demand more from their electronic devices. For example longer lasting and safe batteries, high resolution LCD, smaller and smarter PCBs etc. Malvern Panalytical has multiple analytical solutions for batteries, LCDs, wafers, printed circuit boards and more. This is so you have high performance yet safe and compliant electronic products.
Read more about our solutions below:

Prevent battery plates from wearing out easily by monitoring the particle size distribution and packing density with the Mastersizer laser diffraction technique.
Batteries having issues with recharging? The Gailpix3D XRD detector uses X-ray diffraction and computed tomography to …

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Insitec, Laser Diffraction, Mastersizer, Meet the Experts, Particle size »

[5 Oct 2017 | ]

The heavy cost of mining and minerals manufacturing
The importance of minerals as a production resource applies to many facets of our daily lives. For instance, the quality of concrete determines the smoothness of a road surface and the sturdiness of a building. However, with the ever-growing demands for quality cement, many have spurred manufacturing processes leading to hefty costs. Such costs incurred comes from wastage when having to reproduce cement because it does not meet the quality standard.
Based on a mechanical and civil engineering study, 6-15% of construction costs …

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Dynamic Light Scattering, Electrophoretic light scattering, Laser Diffraction, Particle size, Zeta potential, Zetasizer »

[3 Aug 2017 | ]

Intralipid-Lipid emulsions

Lipid emulsions are administered intravenously for a variety of purposes:

To help feed patients with temporary difficulty in ingesting food orally
For better transport of lipophilic drugs (fat-friendly active ingredient (API) which is not soluble in water)
For controlled release of drugs (size related to uptake and retention)
To decreasing adverse reactions to drugs
To improve targeting of drugs
In emerging gene therapies for cellular and gene delivery, and personalized medicine

Control and understanding of colloidal properties – such as droplet size and zeta potential – enable the design and optimization of appropriately stable emulsions. The …

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Laser Diffraction, Mastersizer, Particle size, Tech Talk »

[1 Aug 2017 | ]

Just when I thought I’d seen everything that could contaminate the background, a user sent me this picture! The Musca Domestica (common housefly) was attracted by certain aromatics used in testing and seems to have entered the measurement cell through an empty Hydro EV over a weekend. Unfortunately, it became wedged within the measurement cell and did not survive the experience.

The most important message from the Mastersizer training courses I give is to make sure you have a good background before you start. Laser diffraction is a background subtracted technique: …

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Laser Diffraction, Mastersizer, Meet the Experts, Particle size, Tech Talk »

[13 Jun 2017 | ]

I recently presented a webinar exploring the practical aspects of sieving method – the advantages and disadvantages.  I compared the method to other techniques such as laser diffraction indicating the increased wealth of information that can be obtained with these more modern instrumental techniques and the common pitfalls and assumptions of the screening technique.
More than 800 of you registered for the webinar and I received a large numbers of interesting questions which I have been working steadily through. I thought it would be a good idea to share the questions and answers via the blog, so here they …

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Français, Insitec, Laser Diffraction, Malvern Panalytical Events, Meet the Experts, Particle shape, Particle size »

[2 May 2017 | ]

Malvern organise des formations en collaboration avec la société SDTech Micro et SDTech Nano, son partenaire technique depuis 7 ans.

SDTech Micro, situé à Alès, est spécialisé dans l’analyse et le traitement à façon des poudres fines et ultrafines.
La semaine derniere, SDtech organisait les journees techniques avec Glatt et Malvern. Des présentations théoriques s’enchainerent avec des ateliers sur un granulateur Glatt en mode “granulation” le premier jour puis en mode “enrobage” le deuxième jour.

 

En parallèle une démonstration de broyage sur un microniseur à jet d’air contrôlé entièrement par un granulomètre laser …

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Image Analysis, Laser Diffraction, Mastersizer, Morphologi, Tech Talk »

[13 Apr 2017 | ]

The prevalence of chocolate eggs and chocolate bunnies in the supermarkets here in the UK can only signal one thing: Easter is upon us.  With the emergence of daffodils, buds appearing on trees, lambs frolicking in the fields and warmth seeping back into the northern hemisphere, the cold winter months are over.  Of course, it is not just in the western world that the arrival of spring, new life and new beginnings are celebrated.
In Japan, a country I had the pleasure of living in for a year and a half …

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Français, Insitec, Laser Diffraction, Meet the Experts, Parsum, Particle size, Spatial Filter Velocimetry »

[23 Mar 2017 | ]

“Lit d’air fluidisé : Granulation, Enrobage et Encapsulation”

Malvern, leader en caractérisation des particules, SDTech Micro, expert des poudres fines, et son partenaire technique Glatt, leader mondial en lit d’air fluidisé, organisent deux journées techniques pour aborder les enjeux et les nouveautés technologiques des procédés de granulation, d’enrobage et d’encapsulation en lit d’air fluidisé. Rappels théoriques et ateliers pratiques sont au programme.
THEMATIQUES :
25 avril :

Présentation de SDTech et de Glatt
Lit d’air fluidisé, techniques et technologies
De la poudre aux grains, caractérisation
1er atelier : Granulation en lit d’air fluidisé

26 avril :

Sécurité des poudres …

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Binding affinity and Kd, Differential Scanning Calorimetry, Dynamic Light Scattering, Français, Gel permeation chromatography, Image Analysis, Isothermal Titration Calorimetry, Laser Diffraction, Meet the Experts, Molecular size, Nanoparticle Tracking Analysis, Particle concentration, Particle size, Rheology, Rheometry, Size Exclusion Chromatography, Static Light Scattering, Zeta potential »

[21 Feb 2017 | ]

Afin de vous apporter un support concret pour utiliser votre système de façon optimale, finaliser vos bonnes pratiques de laboratoire et répondre à vos besoins spécifiques, Malvern organise des formations sur site ou en sessions dans nos 3 agences françaises (Orsay, Lyon et Toulouse).
Voici les dates de toutes les sessions programmées pour 2017 :
CARACTERISATION DES PARTICULES PAR DIFFRACTION LASER
Objectifs : Perfectionner les méthodes de caractérisation des particules en voie sèche et liquide, définir les bonnes pratiques de laboratoire et s’adapter aux besoins spécifiques de chaque installation. Comprendre le principe physique …

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Dynamic Light Scattering, Français, Laser Diffraction, Malvern Panalytical Events, Meet the Experts, Nanosight, Particle size, Static Light Scattering, Zetasizer »

[23 Nov 2016 | ]

Les 20èmes rencontres organisées à Rennes auront lieu du 28 au 30 novembre avec la collaboration l’Institut des Sciences Chimiques de Rennes et la plateforme ScanMat. La directrice de cette plateforme, Maryline Guilloux-Viry, nous fera l’honneur d’accueillir les participants et de présenter les moyens et compétences disponibles au sein de la fédération des 5 plateformes constituant ScanMat (Microscopies électroniques, Analyses structurales et élémentaire, Synthèse et mise en forme, Spectroscopies et Microspectroscopies optiques).
Les nanoparticules seront au cœur de ces rencontres avec une évocation des nouvelles réglementations de REACH qui seront en vigueur …

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Dynamic Light Scattering, Laser Diffraction, Mastersizer, Particle size, Tech Talk, Zetasizer »

[25 Aug 2016 | ]

Size distributions are a description of the fact that not every component in the sample has the same size.  There is a range of sizes present, as mathematically described by a distribution.
There are different ways to represent this distribution in terms of:

Intensity – How much light comes from the different components?
Volume or mass – How much volume is present in the different components?
Number – How many particles are present in the different components?

This often causes confusion, and the intensity volume number issue is one of the most popular blogs.
Intuitively …

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Chemical identification, Image Analysis, Laser Diffraction, Malvern Panalytical Events, Mastersizer, Morphologi, Particle shape, Particle size, Raman spectroscopy »

[29 Jun 2016 | ]

Over the past week I’ve had a lot of fun working with Malvern’s team in China to deliver a series of seminars designed to help researchers engaged in pharmaceutical product development. These meetings focused on how Malvern’s material characterization systems can help those developing and manufacturing oral solid dose formulations. During the seminar series, we had the privilege of meeting with well over 200 customers, providing us with the chance to learn about the challenges they are facing in product development, as they seek to select APIs and excipients which …

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