Greetings, Materials Talks readers, from sunny Palm Springs in beautiful Southern California! I wanted to update you on the wonderful conference Malvern has attended here: “Peptalk – The protein science week.”

Peptalk, held each January, is dedicated to the fields of protein and peptide therapeutic development. This year’s event attracted over 1,200 attendees from all over the world. Presentations were divided into seven pipelines covering everything from protein and antibody development, formulation stability, purification and aggregation, all the way to facilities design, manufacturing and packaging.

Malvern was one of 80 suppliers vying for attention in the exhibition hall. Our booth, number 315, featured our new SEC-MALS 20 GPC/SEC detector along with the Zetasizer range of products for measurement of size, molecular weight and protein charge. Conversations were focused around Malvern’s newly-released white paper: Developing a Bioformulation Stability Profile.

ZMV-for-proteins-SEC-LS

Malvern’s Viscosizer 200 system was also on display, offering automated measurement of viscosity and particle size of protein formulations on microliter volumes. We also took the opportunity to reintroduce people to our Zetasizer MicroV product, offering batch and flow mode measurements for both protein size and molecular weight using SLS and DLS techniques.

A key focus of this conference for many attendees was the identification and detection of protein aggregates within therapeutic products. From the simple detection of oligomers and higher order aggregates, to the detection of sub-visible particles within a protein solution, investigation of these particles has become a focus not only for research scientists, but also for the FDA. Attendees were eager to learn of the current capabilities and recent developments Malvern has made in detection and characterization of sub-visible particles.

We were also excited to talk about our new integration with NanoSight, which provides several exciting new additions to Malvern’s product range, all based on the technique of Nano Tracking Analysis (NTA).  This technology is a perfect fit for particles from 10 nm to 2000 nm, and can be used for the detection and quantification of protein aggregates and contaminants within a biotherapeutic sample.

For those of you who couldn’t make it to Peptalk, hopefully you will join us at another conference this year.  During February we will be attending “World Drug Delivery and Formulation 2014” in Berlin, and the “3rd Biotechnology World Congress” in Dubai.

On the same topic

A very Happy New Year in sunny Palm Springs!

GPC course at Pittcon