Congratulations to Professor Kathryn Whitehead at CMU!

 

DNA-RNA_oligonucleotides_16692030_300x270We were delighted to hear that Kathryn Whitehead at Carnegie Mellon University was selected as one of this year’s  “Brilliant Ten” by Popular Science.  She was chosen for her exciting research on nanoparticle drug delivery vehicles involving short (also known as small) interfering ribonucleic acids (siRNAs).

 

 

 

 

Cellular uptake of these delivery agents is affected by their size: in one of Prof. Whitehead’s recent publications ‘Lipidoid Nanoparticles for siRNA Delivery to the Intestinal Epithelium: In Vitro Investigations in a Caco-2 Model‘, nanoparticles with diameters of 110 nm -140 nm were investigated for trans-epithelial delivery. Positive charge interactions with the cell membrane can be harmful, thus a slight negative charge at neutral pH is a design parameter of the lipidoid nanoparticle selection. Both size and charge were measured with the Zetasizer Nano-ZS.

It is great to see nanoparticle research in the headlines. Congratulations and appreciation to the whole Whitehead group.

Continued success with your dynamic and electrophoretic light scattering data!

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