We will be attending Pittcon 2018 in Orlando, Florida Feb 26th – Mar 1st and once again we are pleased to feature a number of our recognized characterization experts who will be presenting a variety of short courses throughout the week.
Time is running out, so don’t miss out on the early bird deadline for discounted admission which ends on February 5th.
Below is a listing of our available short course offerings.
We look forward to seeing you in Orlando at one of our short courses and our Booths #2118 & #2119.
Monday, February 26th
Fundamentals of Particle Size Analysis with an Emphasis on Light Scattering Techniques
Course Number: SC060, 8:30 AM – 5:00 PM – Alan Rawle, Ulf Nobbmann
A 1-day course that will bring newcomers to the particle sizing field up to speed on the basics (including terminology, international standards, and math) of particle size analysis. The main techniques (sieves, sedimentation, electrozone sensing) will be covered but the main emphasis will be on light scattering techniques in particular dynamic light scattering (DLS; 1 – 1000 nm approx.) and laser diffraction (0.1 -3000 microns approx.)
Investigation of Size and Polydispersity of a Nanoparticle Reference Material by DLS
Course Number: 314 – 340-3, 12:00 AM – 12:00 PM – Ana Morfesis, Ulf Nobbmann
This ½ day course explains that nanotechnology continues to gain importance in both fundamental and applied sciences, the need to measure size has grown with it. Of the various techniques available to characterize nanoparticle size (such as atomic force AFM, transmission electron TEM, or scanning electron microscopy SEM, and also small angle X-ray scattering SAXS), we concentrate on dynamic light scattering DLS in this study.
Tuesday, February 27th
Advanced Light Scattering for Optical Rheology: G’ and G’ at High Frequency
Course Number: SC102, 8:30 AM – 12:30 PM – Ulf Nobbmann
This ½ day course covers the principles of optical rheology. Dynamic Light Scattering (DLS) is widely used to obtain particle size. It can also detect the thermally induced mean square displacement (MSD) of tracer particles. This MSD is converted into shear storage and loss modulus G’ and G’ using the generalized Stokes-Einstein equation. DLS micro-rheology can thus probe short time dynamics of weakly structured solutions, complementary to traditional rotational rheology. This may, for example, be used to study the evolution of weak viscoelasticity in the onset of gelation.
The different practical steps (tracer bead selection, size by DLS, zeta potential to check the absence of interaction) are covered with examples. Details of micro-rheology include basics (principle of operation, math, caveats) and example applications in laboratory research
Sampling for Particle Size Analysis
Course Number: SC061, 8:30 AM – 12:30 PM – Alan Rawle
A ½-day course that will bring personnel in the particle sizing field up to speed on the basics and importance of sampling for particle size analysis. The course will deal with 2 main objectives – determination of the minimum mass required for any required precision and the calculation of the best fundamental sampling error (FSE) based on the mass used in any particle size determination. We will point out the major issues with sampling including delimitation errors and provide limited advice as to the recommended routes to take a reasonable sample and the dangers of taking limited or unrepresentative samples. The course is suited to users of all particle size analysis techniques from sieves to light scattering and there will be a practical exercise for attendees.
Size, Molecular Weight and Zeta Potential for Life Science & Nanoscience Applications
Course Number: SC057, 8:30 AM – 12:30 PM – Ana Morfesis
The objectives of this course are to discuss Dynamic Light Scattering (DLS), Nano-particle Tracking Analysis (NTA), Molecular Weight and zeta potential methods. DLS and NTA are versatile and non-destructive measurement techniques that are ideally suited as a metrology of choice for size, stability, and identification of bio-molecules, nano-material, proteins, aggregates and emulsions or suspensions in solution. We will also discuss electrophoretic mobility measurements and the importance of zeta potential in understanding interfacial behavior and the formulation of multi-component products. We will discuss; DLS and NTA, differences between these sizing methods, review theory, provide useful tips for sample preparation and analysis of measurement results, molecular weight and zeta potential.
Wednesday, February 28th
Water Treatment and the Benefits of Light Scattering Characterization
Course Number: SC058, 8:30 AM – 12:30 PM – Ana Morfesis
Drinking water in the US and developed nations of the world is treated to remove contamination of foreign materials, both mineral and organic. Surface water treatment, water remediation, and wastewater treatment are critical issues in providing safe drinking water to an ever-growing world population. Control of turbidity and removal of NOM remains one of the main challenges facing water utilities, especially when changes in source water and equipment issues require rapid action to maintain stable floc formation. One of the requirements for removing or inactivating particulate contaminants as well as biological parasites is to enhance the coagulation capabilities in water treatment facilities. Objectives of this short course are to discuss the role that light scattering, turbidity and zeta potential can play in optimizing water clarification.
Comparative Study of Weighing Methods and Their Effects on the XRF Analytical Results of Iron Ores
Course Number: 205B – 1300-2, 8:50am – 9:10am – Janice Pitre
This study compares the most common weighing techniques used in preparing samples for fusion: catch weight and sample-to-flux ratio. Different weighing precisions have been tested. Manual and automated weighing as well as XRF correction have been compared.
Separations: Fundamentals of Advanced Gel Permeation & Size Exclusion Chromatography Detection – Course Number: SC076, 1:00 PM – 5:50 PM – Mark Pothecary
This ½ day course covers the theoretical and practical principles of GPC & SEC.
Conventional chromatography relies solely on a single concentration detector (RI, UV) to find Mw, Mn, PDI, %aggregation, by comparing the elution volume of a sample to similar known standards. Light overcomes the significant limitations of this technique to provide a direct measurement of ‘absolute’ molecular weight, irrespective of the sample’s chemistry, composition, shape, and structure. This is particularly useful for novel advanced polymers and proteins. The addition of a viscometer detector provides extra information around the intrinsic viscosity, structure, and size of molecules down to the smallest molecular weights.
In combination, these detectors offer a wealth of molecular information about the samples being analyzed.
This course will discuss the principles behind the different detectors and how sample molecular weight and other parameters can be measured. We will also discuss practical aspects of making high-quality GPC/SEC measurements and generating quality results. Finally, we will look at a series of application examples to see how these measurements can be applied to a wide range of applications and samples types.
Thursday, March 1st
Complementary Techniques to Directly Characterize Liposomes: Nanoparticle Tracking Analysis, Dynamic Light Scattering, and Electrophoretic Light Scattering
Course Number: 2160-12, 1:00pm – 3:00pm – Ragy Ragheb
This study looks at optimal conditions for extruding liposomes as well as their stability under different conditions. We` highlight the limit of detection for fluorescently labeled liposomes. Our aim is to further educate the public about the intricacies of liposome formation and characterization as measured by Nanoparticle Tracking Analysis (NTA).
We really look forward to seeing you there soon! Visit Plan Your Pittcon to register for all Malvern Panalytical short courses