Author Archives: Kyle Williams

The primary goal when employing gel permeation / size exclusion chromatography (GPC/SEC) is often to determine the molecular weight of a macromolecular sample.  Multi-detector systems, such as Malvern Panalytical’s OMNISEC and TDAmax systems, are able to offer a range of…READ MORE >

There are many things to consider when maintaining a GPC/SEC instrument: the mobile phase, the column set, the pump components, the post-column filter, and up to four different detectors…all in a single system! And that’s not even accounting for your…READ MORE >

You’ve done the hard parts to get your GPC/SEC instrument ready: prepared the mobile phase, stabilized the detector baselines, and prepared your sample.  After injection and completion of your sample sequence, you have acquired data.  Congrats!  Now, before you even…READ MORE >

Whether your samples are synthetic polymers, natural materials such as polysaccharides, or proteins, antibodies, or other biological samples, gel permeation / size exclusion chromatography (GPC/SEC) is the ideal technique for characterizing those and other types of macromolecules.  The information offered from…READ MORE >

Gel Permeation / Size Exclusion Chromatography is the ideal technique for determining the molecular weight of macromolecules.  In addition to molecular weight, other molecular parameters can be calculated by taking advantage of various detector combinations, such as intrinsic viscosity (IV),…READ MORE >