Author Archives: Stoyan Milev


Published 17 Nov 2015

DSC and the meaning of Tm – DSC protein stability

We can extract multiple thermodynamic parameters from DSC data, such as ΔH, ΔHvH, ΔCp, and ΔG … but the most widely used parameter is Tm. Incidentally this is also the easiest and most accurate value to obtain – it is…READ MORE >

Published 23 Apr 2015

N-value ITC data

Don’t throw away your “bad” N-value ITC data The N-value commonly referred as the stoichiometry is often used as a qualifier for a “good” or “bad” titration. The reasoning goes like this – “if my N-value is 20% or more…READ MORE >

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