Author Archives: Verna Frasca

Verna Frasca received her Ph.D. in Biological Chemistry from the University of Michigan, and did post-doctoral training at New York State Department of Health (Albany) and University of Texas Southwestern Medical Center (Dallas). Dr. Frasca is joined MicroCal in 2001, and is currently the Applications Manager for MicroCal products with Malvern Instruments. Her responsibilities include supporting use of Isothermal Titration Calorimetry (ITC) and Differential Scanning Calorimetry (DSC) in the life sciences and drug discovery and development. Dr. Frasca has extensive experience in protein expression, protein purification, enzymology, biophysical characterization, and molecular biology.

Published 28 Jul 2020

ITC Technical Tip: Merging ITC data files by concatenation

Concatenation (noun) con·cat·e·na·tion plural concatenations Definition of concatenation: a group of things linked together or occurring together in a way that produces a particular result or effect the act of concatenating things or the state of being concatenated : union…READ MORE >

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Published 23 Jun 2020

MicroCal PEAQ-ITC with organic solvents: Tips and cautions

Tips on performing experiments with organic solvents on a MicroCal PEAQ-ITC system, including experimental method adjustment for organic solvents.

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Published 28 May 2020

How to shut down MicroCal instruments for extended storage

When your MicroCal system will not be used for an extended period, these are the recommended procedures for the shutdown of different MicroCal instruments.

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Published 23 Apr 2020

WEBINAR Focus on Pharma – Characterization of Human Soluble Epoxide Hydrolase Kinetics by ITC

Join us on May 14 for a webinar about Isothermal Titration Calorimetry, presented by Professor Conte and Dr. Abis from Kings College, London.

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Published 14 Apr 2020

Summary of Styrene Maleic Acid-lipid particles (SMALP) 2020 conference

Styrene maleic acid-lipid particles (SMALPs) are nanodiscs made from the interaction of membrane bilayers and styrene-maleic acid (SMA) copolymer. SMA and other related amphipathic polymers can spontaneously solubilize membranes to form SMALPs. Since there is no requirement for the conventional detergents…READ MORE >

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