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Elemental quantification

Quantification of elemental concentrations using XRF and PFTNA.

In many industries, a quick screening of sample material of unknown composition is required without having dedicated standards. In such cases, standardless analysis software such as OMNIAN can be used to determine the overall elemental composition and provide semi-quantitative values of the elemental concentrations.

Binding affinity and Kd, Chemical identification, Differential Scanning Calorimetry, Dynamic Light Scattering, Electrophoretic light scattering, Elemental analysis, Elemental quantification, Empyrean, Epsilon, Image Analysis, Isothermal Titration Calorimetry, Laser Diffraction, Malvern Panalytical Events, Mastersizer, MicroCal, Microcalorimetry, Morphologi, Particle shape, Particle size, Tech Talk, X-Ray Diffraction (XRD), X-Ray Fluorescence (XRF), Zetasizer »

[19 Oct 2018 | ]

On October 2, 2018, we held a seminar entitled “Overcoming Characterization Challenges in Drug Formulation” in the Boston area.  It was a great opportunity to meet with many pharmaceutical scientists in the area and learn about their challenges and concerns.  The presentations addressed a number of topics of interest, from stability of formulations, trace phase and impurity detection, deformulation, root cause analysis, to optimizing small molecule candidate screening.  There were great questions from the audience, so we rounded up several questions and answers here to share.
How does the Mastersizer 3000 see …

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Customer experience, Elemental analysis, Elemental quantification, Epsilon, X-Ray Fluorescence (XRF) »

[11 Oct 2018 | ]

Of all the chemical processes in the fine chemical and pharmaceutical industries, cross-coupling reactions are among the most important.  This often involves platinum group metal (PGM) catalysts, which then must be separated from the product to avoid contamination of the product by these regulated elemental impurities (USP<232>), as well as avoiding that these valuable materials enter the waste stream.
Here is where the process chemists step in to save the day, developing methods to scavenge metal catalyst, tailored for effectiveness with each new compound.  This is an iterative process, and metals …

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CubiX³, Elemental quantification, X-Ray Diffraction (XRD), X-Ray Fluorescence (XRF), Zetium »

[7 Jun 2018 | ]

Lower commodity prices, weaker demand, environmental regulations, lower ore grades, and higher running costs are some of the main challenges that the mining industry has to deal with every day. But now is a good time, while activities are off-peak, to adopt sustainable cost control measures beyond the traditional and generate data that will improve productivity and process stability. Reducing C1 cash costs and increasing revenues can be accomplished with the extensive use of automation and robots in the field and in the laboratory, to gain in productivity and remain …

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Elemental analysis, Elemental quantification, Epsilon, Tech Talk, X-Ray Fluorescence (XRF) »

[17 May 2018 | ]

Outdoor air pollution can have many sources, both anthropogenic (power generation, vehicle emissions, industrial and agricultural emissions, etc.) and natural, for instance, volcanic eruption, wind erosion or wildfires.  A key area of concern is the Suspended Particulate Matter (SPM), which can have adverse effects on health, particularly in the particle size ranges under ten microns.  These are further characterized by two designations – PM10 (2.5 – 10 micron) and PM2.5 (<2.5 micron), with PM10 having the ability to penetrate deep into lungs, and PM2.5 able to permeate throughout the body …

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2830 ZT, 3D structure / imaging, Contaminant detection and analysis, Elemental analysis, Elemental quantification, Epsilon, Meet the Experts, X-Ray Fluorescence (XRF), Zetium »

[1 Feb 2018 | ]

For quality and process control many elemental analysis techniques are available. Let’s see how ICP, AAS, ICP-MS, ICP-OES and X-ray fluorescence spectroscopy (XRF) stack up are traditional techniques used in many industries. Each of these techniques has a number of advantages and disadvantages giving the analyst the flexibility to choose which technology suits best. When the required limits of quantification are above 1 ppm (µg/g), or when the non-destructive analysis is required, XRF is a very attractive technique that should be considered, especially when analyzing solids, powders, slurries, filters, and …

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