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Français, Insitec, Laser Diffraction, Mastersizer, Meet the Experts, Particle size »

[15 Nov 2018 | ]

Lundi 26 novembre après-midi & Mardi 27 novembre 2018

Alain Blasco, spécialiste Solutions Process chez Malvern Panalytical, animera l’atelier sur le nanobroyage et le suivi en ligne lors des ateliers techniques organisés par la société SDTech sur leur site d’Alès.

SDTech Micro est spécialisée dans l’analyse et le traitement à façon des poudres fines et ultrafines.
 

Programme

Lundi 26 novembre

13H30
Accueil des participants

14H00
Présentation de la journée technique et des partenaires

14H45
Caractérisation des poudres, propriétés d’usage et techniques analytiques

16H00
Ateliers :

Mesure de la taille – Du millimètre au nanomètre avec démonstrations de diffraction et de diffusion …

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Customer experience, Gel permeation chromatography, OMNISEC, Size Exclusion Chromatography, Tech Talk »

[15 Nov 2018 | ]

While talking to customers about their samples, a frequent topic that comes up is whether or not their samples are branched.  Fortunately, I work primarily with Malvern Panalytical’s gel permeation / size exclusion chromatography (GPC/SEC) product range, which in addition to providing molecular weight, intrinsic viscosity (IV), and hydrodynamic radius (Rh) data, offers the ideal technique to observe, and even quantify, the extent of branching within a sample.  In this post, I’m going to describe what it means for a sample to be branched, how branching affects a sample’s molecular …

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Malvern Panalytical Events, Tech Talk, X-Ray Diffraction (XRD) »

[13 Nov 2018 | ]

Addressing concerns about data quality, space, throughput and user experience
More research institutions are moving towards a central laboratory model of shared analytical equipment. It encourages optimal usage of the technologies, building of expertise in techniques and ensuring the upkeep of better laboratory practices. X-ray diffraction (XRD) is a paramount technique for any material science research project. Therefore, the selection of a correct diffractometer model, suitable for the task, often comes to the top of the priority list, when designing a new laboratory.
As an Application Specialist at Malvern Panalytical, we often …

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Kinexus, Malvern Panalytical Events, Meet the Experts, Rheometry »

[9 Nov 2018 | ]

Commentary, courtesy of Everett Crews (Ingevity), and AMAP
Although the history of the scientific study of the flow of matter is replete with names of our greatest thinkers, from Aristotle, Galileo, and Newton to Maxwell, Edison, and Einstein, the term “rheology,” like the science itself, was arguably born in the early twentieth century. The English-speaking world attributes the creation of the term, “rheology,” to E.C. Bingham and J. R. Crawford in 1929, although the word had been in use in German scientific literature as early as 1901 (the French limnologist, Francois …

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ASD, Customer experience, Near-InfraRed spectroscopy (NIR), QualitySpec, Remote sensing »

[8 Nov 2018 | ]

… using an ASD Vis/NIRS spectrometer
Cassava is a main staple for over 800 million people around the world. Ugochukwu Ikeogu with Cornell University’s College of Agriculture and Life Sciences, conducts research on high throughput phenotyping and genomics-assisted breeding for quality traits in cassava. Ugochukwu is part of the NEXTGEN Cassava project funded by the Bill and Melinda Gates Foundation, and UK Aid has recently published his research work, involving the use of a portable visible-near-infrared (Vis/NIRS) ASD QualitySpec Trek instrument.
Case study
In the PLOS One online publication, “Rapid analyses of dry matter content …

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Laser Diffraction, Mastersizer, Particle size, Tech Talk »

[1 Nov 2018 | ]

Are you pondering which laser diffraction particle size analyzer to use for your scientific research?
Many people consider the number of Google Scholar publication references as an indicator of acceptance of a particular scientific instrument’s technique, performance, and value. The higher the number of publications, the more credibility people tend to offer towards the choice of that instrument for their important research needs.
After doing a search on Google Scholar for references to the Mastersizer 3000 as well as the Mastersizer 2000, and then comparing versus several other models of laser diffraction …

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Customer experience, Laser Diffraction, Particle size, Spraytec »

[31 Oct 2018 | ]

“It’s impossible to know what happens in the fog of war” said a former US Secretary of State.  But the scientists at Sandia Labs in New Mexico are working to fix that, with the help of a Spraytec laser diffraction system.
The Spraytec is used to measure the droplet size of the airborne droplets, to verify the fog being created is an accurate replica of what is found in nature.  By creating fog droplets with a known droplet size, fog environments are created that accurately replicate those found in specific situations. …

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Aeris, X-Ray Diffraction (XRD) »

[25 Oct 2018 | ]

Aeris is the tabletop diffractometer, launched by Malvern Panalytical at the end of 2016. Despite its young age, Aeris has already established its own place in many laboratories and industrial sites worldwide. There are many reasons “why” our users select Aeris for powder X-ray diffraction (XRD) tasks. Some are amazed by the data quality and speed, approaching that of full power floor-standing XRD. Some like the concept of external sample loading preventing possible mistakes by an inexperienced user. Some benefit from the intuitive user interface, virtually eliminating a need for …

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Differential Scanning Calorimetry, Dynamic Light Scattering, Electrophoretic light scattering, Empyrean, MicroCal, Nanosight, Particle concentration, Particle shape, Particle size, Tech Talk, X-Ray Diffraction (XRD), Zeta potential, Zetasizer »

[24 Oct 2018 | ]

Liposomes have been attractive delivery systems for decades due to their composition of natural biological lipids and structural resemblance to cell membranes suggesting metabolic compatibility, low toxicity, biocompatibility and lack of a strong immune response1.  They are comprised of spherical vesicles with an aqueous core enclosed by one or more phospholipid bilayers or lamellae and are frequently classified based on their size, polydispersity, and number of bilayers2. Control over these parameters has remained a challenge with most preparation methods and is further accentuated when moving from a laboratory to industrial …

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ASD, Customer experience, Near-InfraRed spectroscopy (NIR), Remote sensing, TerraSpec, X-Ray Diffraction (XRD) »

[23 Oct 2018 | ]

Please Note: This is a follow-up post to 10 October’s published post titled, “Studying Mars mineralogy on Earth”
By J. Flahaut (1,2), F. Viveiros (3), C. Silva (3,4), V. Rennie (5), J. V. Cruz (3), L. Moreno (3,4), P. Freire (3), M. Minin (6), K. Olsson-Francis (5), A.P. Rossi (6). Dr. Jessica Flahaut is a planetary geologist at CNRS/CPRG Nancy, France. Her fields of expertise include remote sensing and spectroscopic studies of Mars and the Moon, landing site selection and characterization for future missions and terrestrial geology / analog field studies.
(1) CRPG, …

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Binding affinity and Kd, Chemical identification, Differential Scanning Calorimetry, Dynamic Light Scattering, Electrophoretic light scattering, Elemental analysis, Elemental quantification, Empyrean, Epsilon, Image Analysis, Isothermal Titration Calorimetry, Laser Diffraction, Malvern Panalytical Events, Mastersizer, MicroCal, Microcalorimetry, Morphologi, Particle shape, Particle size, Tech Talk, X-Ray Diffraction (XRD), X-Ray Fluorescence (XRF), Zetasizer »

[19 Oct 2018 | ]

On October 2, 2018, we held a seminar entitled “Overcoming Characterization Challenges in Drug Formulation” in the Boston area.  It was a great opportunity to meet with many pharmaceutical scientists in the area and learn about their challenges and concerns.  The presentations addressed a number of topics of interest, from stability of formulations, trace phase and impurity detection, deformulation, root cause analysis, to optimizing small molecule candidate screening.  There were great questions from the audience, so we rounded up several questions and answers here to share.
How does the Mastersizer 3000 see …

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Binding affinity and Kd, Customer experience, Differential Scanning Calorimetry, Isothermal Titration Calorimetry, Malvern Panalytical Events, MicroCal, Tech Talk »

[18 Oct 2018 | ]

The third European MicroCal meeting was held on 13th and 14th September in the beautiful venue of the Institute of Engineering & Technology (IET) at Savoy Place, on the banks of the River Thames in London. We welcomed delegates from across Europe to share and discuss their calorimetry expertise in an agenda packed with excellent scientific presentations.
Day 1
The meeting kicked off with a morning workshop which was repeated in the afternoon session. The workshop’s focus was firmly on data quality and the importance of establishing sample integrity prior to further characterization. This …

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Chemical identification, Image Analysis, Meet the Experts, Morphologi, Particle shape »

[16 Oct 2018 | ]

In this blog post, we look at the history of the software ‘bug’ and explain how not everything that appears to be a software issue is caused by the software itself. With this in mind, we examine how the new design of the Morphologi 4 and Morphologi 4-ID  has helped reduce the risk of environmental issues causing problems which may previously have been mistaken for bugs in the software.  
The term ‘bug’ was used as far back as the 1870s to describe errors or glitches in a system. Early adopters of the …

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Dynamic Light Scattering, Electrophoretic light scattering, Particle size, Tech Talk, Zeta potential, Zetasizer »

[15 Oct 2018 | ]

The new ZS Xplorer software is here!
Modern, flexible and different from the classic Zetasizer software, the novel ZS Xplorer interface was developed specifically for the latest generation of Zetasizer systems: the Zetasizer Pro and the Zetasizer Ultra. If you missed the launch, check out the exciting launch recording and Q&A session.
In order to help you easily adapt to the new interface, here are a few commonly encountered tips to help you become familiar with the entirely new software architecture. The main difference is that data are now saved in one …

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Dynamic Light Scattering, Electrophoretic light scattering, Malvern Panalytical Events, Meet the Experts, Molecular size, Molecular weight, Particle size, Protein Aggregation, Protein Mobility, Static Light Scattering, Tech Talk, Zeta potential, Zetasizer »

[12 Oct 2018 | ]

Join us for the next User group meeting!
User Group Meeting Announcement 19 Oct 2018 1pm-4pm EDT

We are pleased to announce the first virtual Zetasizer User Meeting ZUM-1! This initiative is an effort to foster the diffusion of knowledge and experience between our support group and those researchers that regularly evaluate light scattering data from the Zetasizer. The Zetasizer Users Community is invited to present and share data with specific questions. Get live feedback from our panel of experts.
The meeting will be live-streamed via Webex and is limited to 3.0 hours. …

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Customer experience, Elemental analysis, Elemental quantification, Epsilon, X-Ray Fluorescence (XRF) »

[11 Oct 2018 | ]

Of all the chemical processes in the fine chemical and pharmaceutical industries, cross-coupling reactions are among the most important.  This often involves platinum group metal (PGM) catalysts, which then must be separated from the product to avoid contamination of the product by these regulated elemental impurities (USP<232>), as well as avoiding that these valuable materials enter the waste stream.
Here is where the process chemists step in to save the day, developing methods to scavenge metal catalyst, tailored for effectiveness with each new compound.  This is an iterative process, and metals …

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ASD, Customer experience, FieldSpec, Ground truthing, Near-InfraRed spectroscopy (NIR), Remote sensing »

[10 Oct 2018 | ]

Authored by Dr. Jessica Flahaut (Laboratoire de Géologie de Lyon, France), Dr. Janice Bishop (SETI Institute, California), Mélissa Martinot (VU University Amsterdam, the Netherlands), Nicci Potts (the Open University, United Kingdom and 2015 Goetz Program awardee), Dr. Simone Silvestro (Istituto Nazionale di Astrofisica, Italy) and collaborators G.R. Davies, D. Tedesco, I. Daniel and C. Quantin (see references). 
Dr. Jessica Flahaut is a planetary geologist at CNRS/CPRG Nancy, France. Her fields of expertise include remote sensing and spectroscopic studies of Mars and the Moon, landing site selection and characterization for future missions and …

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Borate fusion, Claisse, Customer experience, »

[9 Oct 2018 | ]

Analyzing glass disks with an X-ray fluorescence (XRF) spectrometer remains the fastest and most convenient method for the chemical analysis of solid samples. However, the investments made in XRF and fusion equipment sometimes not always yield to the expected analytical results and estimated financial pay-offs.
Our experts recently published a white paper that tells you why.
Whether it has to do with inappropriate reference materials, wrong calibration of the XRF, inadequate sample preparation or incompatibility between the fusion instrument and spectrometer, these issues can easily be solved with the help of end-to-end expertise. …

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Kinexus, Meet the Experts, Rheology, Rheometry »

[4 Oct 2018 | ]

The most common approach for measuring time-dependent viscoelastic properties of a material on a rotational rheometer is to perform small amplitude oscillatory shear (SAOS) over a range of oscillation frequencies – commonly referred to as a frequency sweep – where the sample is oscillated back and forth with a given stress or strain. Here the oscillation frequency, measured in rad/s, is equivalent to 1/t, with t the deformation time of the material.
Let’s consider a sample of Play Putty which is a viscoelastic material. At short deformation times (high frequencies) Play …

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Electrophoretic light scattering, Meet the Experts, Protein Aggregation, Protein Mobility, Zeta potential, Zetasizer »

[3 Oct 2018 | ]

Debye Screening – what is it?
 
In colloidal samples (and this spans the whole range from molecules in solution to particles in a dispersion) the movement of and forces between objects are often governed by the charge affecting neighbors. When we measure zeta potential (by electrophoretic light scattering), the determination of the effective charge of particles is really what is probed. In other words: zeta potential (or electrophoretic mobility) is a measure of how the charge of a particle/molecule is influencing the movement of another particle/molecule. The full potential as a …

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