Gel Permeation Chromatography (GPC)


Gel Permeation Chromatography (GPC) is an analytical technique that separates dissolved macromolecules by size based on their elution from columns filled with a porous gel.

From novel polymers to polymer formulations and additives, in applications from paints and coatings to foods and pharmaceuticals, Malvern offers a range of GPC systems or individual GPC detectors including SEC-MALS to suit your application needs.

Published 20 Jun 2019

How does multi-detector GPC/SEC work?

Whether your samples are synthetic polymers, natural materials such as polysaccharides, or proteins, antibodies, or other biological samples, gel permeation / size exclusion chromatography (GPC/SEC) is the ideal technique for characterizing those and other types of macromolecules.  The information offered from…READ MORE >

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Published 30 May 2019

Using GPC/SEC for compositional analysis

Gel Permeation / Size Exclusion Chromatography is the ideal technique for determining the molecular weight of macromolecules.  In addition to molecular weight, other molecular parameters can be calculated by taking advantage of various detector combinations, such as intrinsic viscosity (IV),…READ MORE >

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Published 15 Nov 2018

Can GPC/SEC determine if my sample is branched?

While talking to customers about their samples, a frequent topic that comes up is whether or not their samples are branched.  Fortunately, I work primarily with Malvern Panalytical’s gel permeation / size exclusion chromatography (GPC/SEC) product range, which in addition…READ MORE >

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Published 19 Sep 2018

Which light scattering detector is best for me?

Determining which gel permeation/size exclusion chromatography (GPC/SEC) system is best for your needs can be a daunting task. Even after you’ve decided to include a light scattering detector to obtain absolute molecular weight data you’re still left to choose between…READ MORE >

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Published 12 Sep 2018

The added value of a Malvern Panalytical OMNISEC purchase

When thinking about a reason to purchase a particular piece of scientific equipment, you want to know not only that you are getting the best piece of kit, but also that you’ll be maximizing the return on your investment.  Manufacturers…READ MORE >

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