Microcalorimetry


Characterizing the interactions and stability of biomolecules.

Microcalorimetry is used to study reactions involving biomolecules, including interactions between molecules and conformational changes such as protein folding. Applications range from confirming intended binding targets in small molecule drug discovery to the development of stable biotherapeutics.

Published 8 Jul 2020

How Lucky Am I?

I work at an organization that is behaving with absolute fairness and integrity throughout the pandemic. I have colleagues who have kept our site open, in a safe way, to continue serving our customers. I owe a particularly big ‘Thank…READ MORE >

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Published 23 Jun 2020

MicroCal PEAQ-ITC with organic solvents: Tips and cautions

Tips on performing experiments with organic solvents on a MicroCal PEAQ-ITC system, including experimental method adjustment for organic solvents.

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Published 23 Apr 2020

WEBINAR Focus on Pharma – Characterization of Human Soluble Epoxide Hydrolase Kinetics by ITC

Join us on May 14 for a webinar about Isothermal Titration Calorimetry, presented by Professor Conte and Dr. Abis from Kings College, London.

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Published 11 Feb 2020

SLAS 2020 – How lucky am I?

As a product manager for a range of instruments that serve the drug discovery market, it was a ‘must’ for me to go to San Diego, in January, to attend SLAS2020. It was 40°F warmer than in Massachusetts (where I…READ MORE >

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Published 4 Feb 2020

Save the date: “Advances in Microcalorimetry 2020” – Join us in Bethesda, Maryland this October

Are you: Interested in finding out more about microcalorimetry and how you can apply these tools to advance your biomolecular characterization studies during drug discovery, drug development, or life science research? A new user of Isothermal Titration Calorimetry (ITC) or…READ MORE >

Published 13 Nov 2019

What’s new in ITC: Additions to your (virtual) bookshelf

Use of Isothermal Titration Calorimetry (ITC) continues to grow, and many books and scientific articles cite the use of Malvern Panalytical’s MicroCal ITC systems. This blog highlights recent publications. You can easily use Google Scholar or Scopus to find other…READ MORE >

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Published 16 May 2019

Advances in Microcalorimetry 2019 registration open and call for speakers and posters – Join us in August

On August 7 and 8, 2019, Malvern Panalytical is sponsoring the “Advances in Microcalorimetry 2019” meeting, for Isothermal Titration Calorimetry (ITC) and Differential Scanning Calorimetry (DSC) users.  The meeting is held at the Sheraton Framingham Hotel and Conference Center, in…READ MORE >

Published 18 Apr 2019

Best Practices for Isothermal Titration Calorimetry to study binding interactions – Part 4

Here are several best practices for performing traditional binding experiments with the MicroCal PEAQ-ITC, VP-ITC and iTC200 systems. This is a continuation of previous blogs ‘Best Practices for Isothermal Titration Calorimetry to study binding interactions’ part 1, part 2 and…READ MORE >

Published 16 Apr 2019

Malvern Panalytical in the news

Malvern Panalytical solutions have been featured in several recent online and print articles. The March 2019 edition of ‘American Laboratory’ contains the article “Treat with Heat: Differential Scanning Calorimetry for biology, chemistry, and beyond.’ This article describes how Differential Scanning Calorimetry (DSC)…READ MORE >

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