Microcalorimetry


Characterizing the interactions and stability of biomolecules.

Microcalorimetry is used to study reactions involving biomolecules, including interactions between molecules and conformational changes such as protein folding. Applications range from confirming intended binding targets in small molecule drug discovery to the development of stable biotherapeutics.

Published 30 Jan 2019

Malvern Panalytical’s 2019 US Training Course Schedule

We are pleased to offer several classroom training events for the first half of 2019. Malvern Panalytical instrument users are invited to enroll and attend a course. Learn from our expert technology and product specialists and acquire the skill set…READ MORE >

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Published 29 Jan 2019

First Virtual Malvern Panalytical MicroCal ITC User Meeting – February 28th, 12-3pm ET!

Following our recent successful virtual Zetasizer User meeting back in October 2018, we are pleased to announce the first MicroCal Isothermal Titration (ITC) Virtual User Meeting – Thursday, February 28, 2019, 12:00 to 3:00 PM Eastern Time (ET). This initiative…READ MORE >

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Published 10 Jan 2019

Best Practices for Isothermal Titration Calorimetry to study binding interactions – Part 1

Here are several best practices for performing traditional binding experiments with the MicroCal PEAQ-ITC, VP-ITC and ITC200 systems.    Sample requirements: By convention, the “Macromolecule” is the biomolecule in the isothermal titration calorimeters (ITC) cell, and the “ligand” is the biomolecule…READ MORE >

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Published 8 Jan 2019

Don’t miss your chance to meet protein and particle experts!

The New Year brings a unique opportunity for interaction with key opinion leaders at Malvern Panalytical’s free-to-attend Symposium on Biophysical and Particle Characterization, taking place at Medimmune Cambridge, UK, on February 19th. Please take a look at the event page…READ MORE >

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Published 19 Oct 2018

Overcoming Characterization Challenges in Drug Formulation – Q&A

On October 2, 2018, we held a seminar entitled “Overcoming Characterization Challenges in Drug Formulation” in the Boston area.  It was a great opportunity to meet with many pharmaceutical scientists in the area and learn about their challenges and concerns. …READ MORE >

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