Microcalorimetry


Characterizing the interactions and stability of biomolecules.

Microcalorimetry is used to study reactions involving biomolecules, including interactions between molecules and conformational changes such as protein folding. Applications range from confirming intended binding targets in small molecule drug discovery to the development of stable biotherapeutics.

Published 21 Sep 2017

“Two hundred scientists walked into a bar…”

I know this sounds like the beginning of a bad joke, but in this case, it was actually the beginning of the 2017 Colorado Protein Stability Conference, held in July at Beaver Run Resort in Breckenridge, Colorado. In attendance was…READ MORE >

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Published 4 Jul 2017

Protein Antigens – DSC Journal Club

Protein Antigens and DSC This blog highlights two recent articles that focus on the use of a MicroCal Differential Scanning Calorimetry (DSC) system. Differential Scanning Calorimetry – A Method for Assessing the Thermal Stability and Conformation of Protein Antigen I.B….READ MORE >

Published 23 May 2017

The challenges of reproducibility in life science research

A professional and personal view If your newsfeed from scientific and mainstream media sources is anything like mine, you have seen numerous articles and blogs about the ‘reproducibility crisis’ in the life sciences. Well-established cornerstones of scientific inquiry and research are…READ MORE >

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Published 16 May 2017

Protein Stability Conference is coming to Colorado

With Pre-Conference Workshop on Biophysical Characterization and Particle Analysis   Date: July 17th – 20th. We at Malvern know that protein stability is important in numerous disciplines, ranging from basic and medical biochemistry to pharmaceutical sciences. However, it is rare that…READ MORE >

Published 11 May 2017

European MicroCal Meeting – review and revisit!

In September 2016 Malvern Instruments co-organized a European MicroCal meeting with Institut Pasteur and ARBRE European molecular biophysics network. The meeting was very successful and sparked animated discussions during scientific presentations, panel and poster sessions and interactive workshops.  A key…READ MORE >

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