Size Exclusion Chromatography (SEC)


Size Exclusion Chromatography (SEC or SEC-HPLC) is an analytical technique that separates dissolved macromolecules by size based on their elution from columns filled with a porous gel.

Published 12 Jul 2018

Why do I need a standard if I have a GPC/SEC system with a light scattering detector?

To many people, obtaining molecular weight information from GPC/SEC analysis involves a lengthy calibration process.  A series of standards of known molecular weight are analyzed and a calibration curve based on the standards’ retention volume is generated.  This can be…READ MORE >

Tags:

Published 13 Jun 2018

3rd European MicroCal meeting – Join us in London this September for 2 days of analytical bioscience!

The time is fast arriving for the third in our highly successful series of European MicroCal meetings! This year the meeting is organized by Malvern Panalytical alongside a Scientific Committee of expert users from academia and industry, all with the support of…READ MORE >

Tags: ,

Published 5 Dec 2017

WINN – Innovation for pharmaceutical products

It was my great pleasure to present as part of the Worcestershire Innovation Network at their WINN Wednesday event on the 22nd of November, showcasing the best in innovation across Worcestershire. This included a local company which makes artificial kneecaps and hips, an…READ MORE >

Tags: ,

Published 23 Oct 2017

Polydispersity – what does it mean for DLS and chromatography?

The term polydispersity (or more recently dispersity without the poly, as per IUPAC recommendation) is used to describe the degree of “non-uniformity” of a distribution.  In the field of molecular/nanoparticular characterization, there are in principle two different definitions of polydispersity,…READ MORE >

Tags: , , , ,

Published 21 Sep 2017

“Two hundred scientists walked into a bar…”

I know this sounds like the beginning of a bad joke, but in this case, it was actually the beginning of the 2017 Colorado Protein Stability Conference, held in July at Beaver Run Resort in Breckenridge, Colorado. In attendance was…READ MORE >

Tags: , ,

Subscribe