Tag Archives: gpc/sec


Published 25 Mar 2020

Practice makes perfect

Do you want an OMNISEC but don’t have one yet?  Do you want to practice so you’re ready once your OMNISEC is installed? Or are you simply looking for a way to gain more experience with the OMNISEC software?  If…READ MORE >

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Published 28 Jan 2020

Catching up with OMNISEC!

Scientific research is constantly expanding the scope of human knowledge at academic institutes, businesses, and elsewhere across the globe.  Malvern Panalytical is proud to play a role in this incredible work, with the goal of making sophisticated measurements and analyses…READ MORE >

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Published 3 Sep 2019

Help! I need some…GPC/SEC expert advice

There are many things to consider when maintaining a GPC/SEC instrument: the mobile phase, the column set, the pump components, the post-column filter, and up to four different detectors…all in a single system! And that’s not even accounting for your…READ MORE >

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Published 20 Jun 2019

How does multi-detector GPC/SEC work?

Whether your samples are synthetic polymers, natural materials such as polysaccharides, or proteins, antibodies, or other biological samples, gel permeation / size exclusion chromatography (GPC/SEC) is the ideal technique for characterizing those and other types of macromolecules.  The information offered from…READ MORE >

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Published 30 May 2019

Using GPC/SEC for compositional analysis

Gel Permeation / Size Exclusion Chromatography is the ideal technique for determining the molecular weight of macromolecules.  In addition to molecular weight, other molecular parameters can be calculated by taking advantage of various detector combinations, such as intrinsic viscosity (IV),…READ MORE >

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Published 15 Nov 2018

Can GPC/SEC determine if my sample is branched?

While talking to customers about their samples, a frequent topic that comes up is whether or not their samples are branched.  Fortunately, I work primarily with Malvern Panalytical’s gel permeation / size exclusion chromatography (GPC/SEC) product range, which in addition…READ MORE >

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Published 19 Sep 2018

Which light scattering detector is best for me?

Determining which gel permeation/size exclusion chromatography (GPC/SEC) system is best for your needs can be a daunting task. Even after you’ve decided to include a light scattering detector to obtain absolute molecular weight data you’re still left to choose between…READ MORE >

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Published 22 Aug 2018

What is a dn/dc value and why is it important for GPC/SEC?

The most common detector in any GPC/SEC instrument is a refractive index (RI) detector.  There are multiple reasons for this, but the most important is because the difference in refractive index between that of a sample solution and that of…READ MORE >

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Published 24 Jul 2018

Why does my viscometer signal have a negative peak?

If you’ve ever analyzed GPC/SEC data collected on your OMNISEC or TDA 305 instrument that included a viscometer detector, you might have observed and wondered about a negative peak that elutes in the viscometer signal long after the sample peak. …READ MORE >

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