Tag Archives: light scattering


Published 9 Sep 2021

SEC-MALS 20: upgrade your system!

I spill a lot of digital ink extolling the virtues of our OMNISEC system, and for good reason!  The power of a complete, advanced detection SEC system is undeniable.  But in this post, I’m going to focus on a single,…READ MORE >

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Published 15 Jun 2021

Laser Diffraction for Particle Sizing – Sample Concentration/Dilution (2)

In my last blog, we covered: Why does sample concentration matter? How will it affect results? What is the right concentration range to be measured? Here, we will continue the discussion on: 4. How to prepare and control the sample…READ MORE >

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Published 11 May 2021

Laser Diffraction for Particle Sizing – Sample Concentration/Dilution (1)

“We need to characterize particle size distribution quickly and statically. The estimated size range falls into that covered by laser diffraction. Now what?” Now – sample preparation: Can we actually prepare the samples to be measured properly? When it comes…READ MORE >

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Published 6 May 2021

Aggregates! And what they look like in GPC/SEC data

One of the pleasures of working in the Applications Lab is that I get to analyze a variety of GPC/SEC sample types.  I can be finishing up a set of biodegradable polyesters, currently running low molecular weight oligomers, while getting…READ MORE >

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Published 28 Jan 2021

Laser Diffraction for Particle Sizing – Theory Simply Explained in One Figure

Of course. We have very well written notes and instructions. And with our help on method developments, cases are rare when we ponder on the fundamental theories behind the technology of Mastersizer 3000. Nevertheless, we will need to troubleshoot, to…READ MORE >

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Published 5 May 2020

A Lignin Case Study with the Zetasizer Ultra

Lignin solvated in zwitterionic Good’s buffers displays antibacterial synergy against Staphylococcus aureus What is lignin? Lignin is a versatile aromatic polymer that forms key structural materials in plants and some algae.  They can be used in a wide range of…READ MORE >

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Published 20 Jun 2019

How does multi-detector GPC/SEC work?

Whether your samples are synthetic polymers, natural materials such as polysaccharides, or proteins, antibodies, or other biological samples, gel permeation / size exclusion chromatography (GPC/SEC) is the ideal technique for characterizing those and other types of macromolecules.  The information offered from…READ MORE >

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Published 19 Sep 2018

Which light scattering detector is best for me?

Determining which gel permeation/size exclusion chromatography (GPC/SEC) system is best for your needs can be a daunting task. Even after you’ve decided to include a light scattering detector to obtain absolute molecular weight data you’re still left to choose between…READ MORE >

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Published 21 Jun 2018

Exploring new and exciting applications for multi-detector UPLC

Almost always, my favorite thing about working for a scientific technology company is getting to work on the latest technologies and learn about the applications available to them.  We’re fortunate enough to see the newest technology and play with the…READ MORE >

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