Tag Archives: molecular weight


Published 13 Aug 2019

Can my GPC/SEC chromatogram be trusted?

You’ve done the hard parts to get your GPC/SEC instrument ready: prepared the mobile phase, stabilized the detector baselines, and prepared your sample.  After injection and completion of your sample sequence, you have acquired data.  Congrats!  Now, before you even…READ MORE >

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Published 20 Jun 2019

How does multi-detector GPC/SEC work?

Whether your samples are synthetic polymers, natural materials such as polysaccharides, or proteins, antibodies, or other biological samples, gel permeation / size exclusion chromatography (GPC/SEC) is the ideal technique for characterizing those and other types of macromolecules.  The information offered from…READ MORE >

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Published 21 Jun 2018

Exploring new and exciting applications for multi-detector UPLC

Almost always, my favorite thing about working for a scientific technology company is getting to work on the latest technologies and learn about the applications available to them.  We’re fortunate enough to see the newest technology and play with the…READ MORE >

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Published 2 Nov 2017

Guide to molecular weight – with the Zetasizer

Molecular weight measurements with the Zetasizer software? First a few words of caution: molecular weight or Mw measurements in general are not easy, require time, good sample preparation skills as well as patience. If you are new to the Malvern…READ MORE >

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Published 23 Oct 2017

Polydispersity – what does it mean for DLS and chromatography?

The term polydispersity (or more recently dispersity without the poly, as per IUPAC recommendation) is used to describe the degree of “non-uniformity” of a distribution.  In the field of molecular/nanoparticular characterization, there are in principle two different definitions of polydispersity,…READ MORE >

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