Published 21 Apr 2016
“I’m looking to study the aggregation kinetics of my nanoparticles using the Zetasizer Nano ZS. Is there a way to make time-resolved size measurements using this instrument?” The Zetasizer has become a fairly standard sizing tool for nanoparticles, as it…READ MORE >
Tags: aggregation, dissolution, fibril formation, flowmode, kinetics
Published 19 Nov 2015
Polymer solution rheology to protein aggregation – Following Sir G.I. Taylor In a very fortuitous way indeed, from my academic research at Bristol University through to my work here at Malvern, I have managed to maintain a connection with the brilliant…READ MORE >
Tags: protein aggregation, protein size, rheology, taylor dispersion analysis, viscosizer
Published 21 May 2015
We recently published a new application note on protein characterization using our latest SEC system, OMNISEC, and I wanted to bring your attention to this elegant piece of work that beautifully shows the kind of information you can get from…READ MORE >
Tags: chromatogram, gel permeation chromatography, GPC, IV, molecular weight
Published 24 Feb 2015
I recently took part in a question and answer session with BioPharm International about techniques for measuring and characterizing protein aggregates. The full discussion can be viewed here, however I thought I would also use this blog post to summarize…READ MORE >
Tags: buoyant mass, dynamic light scattering, FDA, morphologi G3-ID, Nanoparticle Tracking Analysis
Published 28 Jul 2014
Our portfolio of instruments to aid in biopharmaceutical research has grown significantly in recent years, thanks to innovation from our Bioscience Development Initiative as well as acquisitions of NanoSight, Viscotek and most recently, MicroCal. As a result,the amount of useful…READ MORE >
Tags: biotherapeutic, Calorimetry, DLS, forumulation stability, isothermal titration calorimetry
Published 24 Jul 2014
Thank you to everyone who joined us on 26th June, for the webinar “Protein Aggregation – Bridging the SubMicron Gap.” We held this webinar because we know that the formation of protein aggregates is a particular concern for parenteral administration biopharmaceuticals due…READ MORE >
Tags: mass, Particle size, protein aggregation, Resonant Mass Measurement, subvisible particles
Published 27 Mar 2014
A perk of working for a company that sells products all over the world is being able to travel without paying for it. Since the end of January I have been visiting customers and attending meetings and seminars on 3…READ MORE >
Tags: distributor, nanosight, NTA, protein aggregation, proteins
Published 28 Jan 2014
Greetings, Materials Talks readers, from sunny Palm Springs in beautiful Southern California! I wanted to update you on the wonderful conference Malvern has attended here: “Peptalk – The protein science week.” Peptalk, held each January, is dedicated to the fields…READ MORE >
Tags: conference, nanosight, peptalk, protein aggregation, proteins
Published 18 Jul 2013
This year marks the 27th anniversary of the Annual meeting of the Protein Society taking place in Boston, MA from 20-23 July. We are delighted to be present at the exhibit and look forward to meeting you there. Exhibit hours are scheduled…READ MORE >
Tags: DLS, dynamic light scattering, protein, protein aggregation, protein society