Tag Archives: sec-mals


Published 10 Mar 2021

GPC/SEC standards from the eStore!

In my last post, I highlighted the most common GPC/SEC columns available from the Malvern Panalytical eStore.  Just like with columns, scientists rely on the selection of appropriate GPC/SEC standards to generate reliable methods and obtain quality results.  In order…READ MORE >

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Published 25 Sep 2019

Rh or Rg: Which is best for my GPC/SEC samples?

The primary goal when employing gel permeation / size exclusion chromatography (GPC/SEC) is often to determine the molecular weight of a macromolecular sample.  Multi-detector systems, such as Malvern Panalytical’s OMNISEC and TDAmax systems, are able to offer a range of…READ MORE >

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Published 13 Aug 2019

Can my GPC/SEC chromatogram be trusted?

You’ve done the hard parts to get your GPC/SEC instrument ready: prepared the mobile phase, stabilized the detector baselines, and prepared your sample.  After injection and completion of your sample sequence, you have acquired data.  Congrats!  Now, before you even…READ MORE >

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Published 19 Sep 2018

Which light scattering detector is best for me?

Determining which gel permeation/size exclusion chromatography (GPC/SEC) system is best for your needs can be a daunting task. Even after you’ve decided to include a light scattering detector to obtain absolute molecular weight data you’re still left to choose between…READ MORE >

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Published 22 Aug 2018

What is a dn/dc value and why is it important for GPC/SEC?

The most common detector in any GPC/SEC instrument is a refractive index (RI) detector.  There are multiple reasons for this, but the most important is because the difference in refractive index between that of a sample solution and that of…READ MORE >

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Published 24 Jul 2018

Why does my viscometer signal have a negative peak?

If you’ve ever analyzed GPC/SEC data collected on your OMNISEC or TDA 305 instrument that included a viscometer detector, you might have observed and wondered about a negative peak that elutes in the viscometer signal long after the sample peak. …READ MORE >

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Published 12 Jul 2018

Why do I need a standard if I have a GPC/SEC system with a light scattering detector?

To many people, obtaining molecular weight information from GPC/SEC analysis involves a lengthy calibration process.  A series of standards of known molecular weight are analyzed and a calibration curve based on the standards’ retention volume is generated.  This can be…READ MORE >

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Published 9 May 2018

Journée sur la chromatographie à Lyon

Atelier dans notre agence de Lyon mardi 12 juin Journée sur la chromatographie d’exclusion de taille pour les protéines (ou de perméation de gel pour les polymères) dans notre agence de Lyon. Vous seront présentés différents systèmes de détection UV, réfractomètre,…READ MORE >

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Published 25 Mar 2015

Perfecting Polymer Measurements: OMNISEC Q&A

A couple of weeks ago I had the opportunity to present a live webinar through Chemical & Engineering News about how our latest solution for Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC), OMNISEC, can help our customers with their synthetic polymer…READ MORE >

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