Tag Archives: SEC


Published 13 Aug 2019

Can my GPC/SEC chromatogram be trusted?

You’ve done the hard parts to get your GPC/SEC instrument ready: prepared the mobile phase, stabilized the detector baselines, and prepared your sample.  After injection and completion of your sample sequence, you have acquired data.  Congrats!  Now, before you even…READ MORE >

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Published 23 Oct 2017

Polydispersity – what does it mean for DLS and chromatography?

The term polydispersity (or more recently dispersity without the poly, as per IUPAC recommendation) is used to describe the degree of “non-uniformity” of a distribution.  In the field of molecular/nanoparticular characterization, there are in principle two different definitions of polydispersity,…READ MORE >

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Published 4 Apr 2017

Malvern’s Top Content Q1 2017

You all know now that at Malvern, we like producing regular content which is dedicated to you, depending if you are a student, researcher or scientist. I really hope that this new Top Content from the last quarter will help…READ MORE >

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Published 6 Aug 2015

Proteasome20S filled with CytochromeC

Looking over an old powerpoint file from Viscotek, an interesting slide on a unique application stood out. Investigating samples of the 20S Proteasome by light scattering in conjunction with refractive index RI was able to clearly determine whether a particular…READ MORE >

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Published 14 Jul 2015

Multi-detector SEC

Multi-detector SEC – 10 reasons why protein scientists need one In a previous post I listed the top ten reasons why a polymer characterization scientist might want to upgrade to multi-detector Gel Permeation Chromatography/Size Exclusion Chromatography, but there are similar…READ MORE >

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